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C5 gene
Known as:
C5a anaphylatoxin
, C5b
, prepro-C5
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Human C5 wild-type allele is located within 9q33-q34 and is approximately 98 kb in length. This allele, which encodes complement C5 protein, is…
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National Institutes of Health
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Related topics
Related topics
10 relations
C5AR1 gene
C5a Anaphylatoxin, human
Chemotaxis
Complement Activation
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
A small-molecule inhibitor of C 5 complement protein
Keith Jendza
,
M. Salcius
,
+21 authors
K. Anderson
2019
Corpus ID: 199459565
1Global Discovery Chemistry, Novartis Institutes of Biomedical Research, Cambridge, MA, USA. 2Chemical Biology and Therapeutics…
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2017
2017
Repeat Measurements of Complement proteins C3a and C5a in COPD patients
T. Southworth
,
C. Pattwell
,
+7 authors
Dave Singh
2017
Corpus ID: 80495223
Background: Complement proteins C3a and C5a are chemoattractants for neutrophils and macrophages, and may increase these cells in…
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2016
2016
Effective suppression of C 5 a-induced proin fl ammatory response using anti-human C 5 a repebody
D. Hwang
,
J. Choi
,
+4 authors
Hak-Sung Kim
2016
Corpus ID: 27636624
The strongest anaphylatoxin, C5a, plays a critical role in the proinflammatory responses, causing the pathogenesis of a number of…
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2008
2008
Erratum: Structure of and influence of a tick complement inhibitor on human complement component 5
F. Fredslund
,
N. Laursen
,
+8 authors
G. Andersen
Nature Immunology
2008
Corpus ID: 6790188
2007
2007
Weak response of porcine C5a receptor towards human C5a in miniature pig endothelial cells and PMNs
K. Yi
,
Sukmook Lee
,
+12 authors
C. Ahn
Xenotransplantation
2007
Corpus ID: 35700350
Abstract: Background: The anaphylatoxin C5a is a potent inflammatory molecule generated during complement activation. Although…
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2002
2002
Inhibiteur de la voie du complement se fixant a c5 et a c5a sans empecher la formation de c5b
Michael S. C. Fung
,
Cecily R. Y. Sun
,
Meisheng Lu
,
William N. C. Sun
2002
Corpus ID: 90383552
La presente invention concerne des inhibiteurs qui se fixent a C5 et a C5a mais qui n'empechent ni l'activation de C5 ni la…
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2001
2001
Characterization of Human C 4 a Anaphylatoxin *
Jeffrey
,
GorskiS
,
Tony
,
Hugli
,
Hans J. Muller-Eberhardg
2001
Corpus ID: 34986206
Human C4a anaphylatoxin was isolated from a CIS digest of the four th component of complement. Isolation required a two-step…
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1987
1987
Patients with bone marrow failure demonstrate decreased cutaneous reactivity to human C5a.
K. Yancey
,
L. Bielory
,
R. Wright
,
N. Young
,
M. Frank
,
T. Lawley
Journal of Investigative Dermatology
1987
Corpus ID: 21350003
In vivo studies have shown that human C5a, a potent complement-derived anaphylatoxin and chemoattractant, produces immediate…
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1986
1986
Demonstration of leukotriene B4 in the scale extracts of psoriasis and inflammatory pustular dermatoses. Correlation with leukocyte chemotactic activity and C5a anaphylatoxin.
Hideaki Takem Atsu
,
Tadashi TERUl
,
Hachiro Tagami
Acta Dermato-Venereologica
1986
Corpus ID: 33773220
We carried out quantification of the levels of leukotriene B4 (LTB4), a highly potent cell membrane-derived leukocyte chemotactic…
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1981
1981
The conversion of human complement component C5 into fragment C5b by the alternative-pathway C5 convertase.
R. Discipio
Biochemical Journal
1981
Corpus ID: 44996156
The cleavage of human complement component C5 to fragment C5b by the alternative pathway C5 convertase was studied. The…
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