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Complement C5 Convertase, Classical Pathway
Known as:
Classical Pathway C5 Convertase
, Complement C5 Convertase, Classical Pathway [Chemical/Ingredient]
, C5 Convertase (C4b2a3b)
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A serine protease that cleaves multiple COMPLEMENT 5 into COMPLEMENT 5A (anaphylatoxin) and COMPLEMENT 5B in the CLASSICAL COMPLEMENT ACTIVATION…
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National Institutes of Health
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Related topics
Related topics
8 relations
CDK5RAP1 gene
Process of secretion
antagonists & inhibitors
aspects of radiation effects
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Broader (1)
Immunologic Factors
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
Complement C3 and C4 and Metabolic Syndrome
M. Copenhaver
,
Chack-Yung Yu
,
R. Hoffman
2017
Corpus ID: 13054171
The complement system is part of the innate immune system and plays a role in regulating inflammation. Increased inflammation is…
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2015
2015
Complement system specifically C5a receptor, inflammation and hypertrophic cardiomyopathy (HCM) in cats
K. H. Khor
2015
Corpus ID: 90649536
The complement cascade is a unique sequence of molecular events occurring within the vascular system in which inactive plasma…
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2010
2010
This information is current as Bone Loss Is Required for Induction of Periodontal and Porphyromonas gingivalis Clearance of Dependent − The C 5 a Receptor Impairs IL-12 Hajishengallis
S. Liang
,
Jennifer L. Krauss
,
+7 authors
G. Hajishengallis
2010
Corpus ID: 236506478
2001
2001
Localization of the Covalent C 3 b-binding Site on C 4 b within the Complement Classical Pathway C 5 Convertase , C 4 b 2 a 3 b *
Haruo
,
KozonoS
,
+14 authors
InoueS
2001
Corpus ID: 34307787
C5 convertase of the classical complement pathway is a trimolecular protein complex consisting of C4b, CZa, and C3b. In the…
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1993
1993
Hemolysis of normal human erythrocytes by autologous serum complement.
H. Kitamura
,
Akiko Nagano
,
E. Kitano
International Archives of Allergy and Immunology
1993
Corpus ID: 46757520
Unsensitized normal human erythrocytes (E) were shown to be lysed when incubated with autologous serum in the presence of zymosan…
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1985
1985
[Binding of activated C3b component with complement effector].
L. Kozlov
,
L. I. Rostovtseva
,
T. S. Lomaka
,
N. S. Sutovskaia
Bioorganicheskaia khimiia
1985
Corpus ID: 3130089
Various nucleophilic agents (acceptors) react with thiolester group of nascent activated fragment (C3b) of the third complement…
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1983
1983
Surface-dependent modulation by H of C5 cleavage by the cell-bound alternative pathway C5 convertase of human complement.
E. Fischer
,
M. Kazatchkine
Journal of Immunology
1983
Corpus ID: 38800120
Regulation by H of formation of the C3 and C5 alternative pathway convertases of complement on cells is dependent on such…
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1983
1983
Inflammatory stimuli augment synthesis of complement component C3 by macrophages
H. Hartung
,
D. Bitter‐Suermann
,
U. Hadding
Agents and Actions
1983
Corpus ID: 43685481
tase sites P(C3b)nBb were formed by reacting EC3b cells with variable amounts of B in the presence of excess P and D. C5…
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1981
1981
The conversion of human complement component C5 into fragment C5b by the alternative-pathway C5 convertase.
R. Discipio
Biochemical Journal
1981
Corpus ID: 44996156
The cleavage of human complement component C5 to fragment C5b by the alternative pathway C5 convertase was studied. The…
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