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Combined Modality Therapy
Known as:
Treatment, Multimodal
, concurrent therapy
, Therapies, Combined Modality
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The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY…
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National Institutes of Health
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Related topics
Related topics
7 relations
Antineoplastic Combined Chemotherapy Protocols
interdisciplinary collaboration
nursing therapy
standards characteristics
Narrower (2)
Combination Drug Therapy
combination cancer therapy
Broader (1)
Therapeutic procedure
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Nivolumab and ipilimumab versus ipilimumab in untreated melanoma.
M. Postow
,
J. Chesney
,
+18 authors
F. Hodi
New England Journal of Medicine
2015
Corpus ID: 205097546
BACKGROUND In a phase 1 dose-escalation study, combined inhibition of T-cell checkpoint pathways by nivolumab and ipilimumab was…
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Highly Cited
2013
Highly Cited
2013
Nivolumab plus ipilimumab in advanced melanoma.
J. Wolchok
,
H. Kluger
,
+21 authors
M. Sznol
New England Journal of Medicine
2013
Corpus ID: 205095555
BACKGROUND In patients with melanoma, ipilimumab (an antibody against cytotoxic T-lymphocyte-associated antigen 4 [CTLA-4…
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Highly Cited
2010
Highly Cited
2010
Infliximab, azathioprine, or combination therapy for Crohn's disease.
J. Colombel
,
W. Sandborn
,
+10 authors
P. Rutgeerts
New England Journal of Medicine
2010
Corpus ID: 19632988
BACKGROUND The comparative efficacy and safety of infliximab and azathioprine therapy alone or in combination for Crohn's disease…
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Review
2006
Review
2006
Lapatinib plus capecitabine for HER2-positive advanced breast cancer.
C. Geyer
,
J. Forster
,
+15 authors
D. Cameron
New England Journal of Medicine
2006
Corpus ID: 42163861
BACKGROUND Lapatinib, a tyrosine kinase inhibitor of human epidermal growth factor receptor type 2 (HER2, also referred to as…
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Highly Cited
2003
Highly Cited
2003
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia.
S. O’Brien
,
F. Guilhot
,
+22 authors
B. Druker
New England Journal of Medicine
2003
Corpus ID: 20464466
BACKGROUND Imatinib, a selective inhibitor of the BCR-ABL tyrosine kinase, produces high response rates in patients with chronic…
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Highly Cited
2003
Highly Cited
2003
Neoadjuvant chemotherapy plus cystectomy compared with cystectomy alone for locally advanced bladder cancer.
H. Grossman
,
R. Natale
,
+8 authors
E. Crawford
New England Journal of Medicine
2003
Corpus ID: 42913929
BACKGROUND Despite aggressive local therapy, patients with locally advanced bladder cancer are at significant risk for metastases…
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Highly Cited
1999
Highly Cited
1999
Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy
D. Finzi
,
J. Blankson
,
+14 authors
R. Siliciano
Nature Network Boston
1999
Corpus ID: 30573138
Combination therapy for HIV-1 infection can reduce plasma virus to undetectable levels, indicating that prolonged treatment might…
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Highly Cited
1998
Highly Cited
1998
Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators.
F. Palella
,
K. Delaney
,
+5 authors
S. Holmberg
New England Journal of Medicine
1998
Corpus ID: 40017032
BACKGROUND AND METHODS National surveillance data show recent, marked reductions in morbidity and mortality associated with the…
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Highly Cited
1998
Highly Cited
1998
Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group.
J. McHutchison
,
S. Gordon
,
+7 authors
J. Albrecht
New England Journal of Medicine
1998
Corpus ID: 11861009
BACKGROUND Only 15 to 20 percent of patients with chronic hepatitis C have a sustained virologic response to interferon therapy…
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Highly Cited
1996
Highly Cited
1996
A comparison of multimodal therapy and surgery for esophageal adenocarcinoma.
T. Walsh
,
N. Noonan
,
D. Hollywood
,
A. Kelly
,
N. Keeling
,
T. Hennessy
New England Journal of Medicine
1996
Corpus ID: 24982255
BACKGROUND Uncontrolled studies suggest that a combination of chemotherapy and radiotherapy improves the survival of patients…
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