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Palytoxin: A New Marine Toxin from a Coelenterate
Palytoxin has been isolated from the zoanthids "limu-make-o-Hana" (Tentatively identified as Palythoa sp.) as a noncrystalline, chromatographically pure entity and is the most highly toxic substance known. Expand
Structure and absolute stereochemistry of hectochlorin, a potent stimulator of actin assembly.
Hectochlorin shows both a unique profile of cytotoxicity by the COMPARE algorithm and potent inhibitory activity toward the fungus Candida albicans. Expand
Isolation and structure/activity features of halomon-related antitumor monoterpenes from the red alga Portieria hornemannii.
Ten halogenated monoterpenes related to the novel antitumor compound halomon or to the carbocyclic analog 7 have been isolated from different geographic collections of the red alga, Portieria hornemannii, providing some interesting initial insights into the structure/activity relationships in this series. Expand
Salmahyrtisol A, a novel cytotoxic sesterterpene from the Red Sea sponge Hyrtios erecta.
The lipophilic partition of a methanol extract of the Red Sea sponge Hyrtios erecta yielded a novel pentacyclic sesterterpene ester salmahyrtisol A, which shows significant cytotoxicity to murine leukemia, human lung carcinoma, and human colon carcinoma. Expand