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Clozapine
Known as:
Clozapinum
, Clozapin
, 5H-Dibenzo(b,e)(1,4)diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)-
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A tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays…
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National Institutes of Health
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Related topics
Related topics
40 relations
Adrenergic alpha-Antagonists [MoA]
Bipolar Disorder
CYP1A2 protein, human
Clozapine 100 MG Oral Tablet
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Broader (6)
Antipsychotic Agents
Benzodiazepine
Benzodiazepines
Carbamazepine
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Narrower (8)
Clozaril
JL 13 compound
JL 18
Leponex
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Early relapse after sudden withdrawal or dose reduction of clozapine
A. Perényi
,
E. Kuncz
,
G. Bagdy
Psychopharmacology
2004
Corpus ID: 9413263
Case 1 was a 24-year-old schizophrenic male who had been hospitalized three times before. On his previous admissions he had shown…
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2004
2004
Supersensitivity and clozapine withdrawal
K. Eklund
Psychopharmacology
2004
Corpus ID: 27164978
The paper from Ekblom et al. (1984) and a report by Perenyi et al. (1985) on rapid relapse in schizophrenia after abrupt…
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Highly Cited
2003
Highly Cited
2003
High-performance liquid chromatography-atmospheric pressure photoionization/tandem mass spectrometric analysis for small molecules in plasma.
Y. Hsieh
,
K. Merkle
,
Ganfeng Wang
,
J. Brisson
,
Walter A. Korfmacher
Analytical Chemistry
2003
Corpus ID: 27734435
A generic high-performance liquid chromatography (HPLC) system interfaced with an atmospheric pressure photoionization (APPI…
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1997
1997
Clozapine in hemiballismus: report of two cases.
Marina Stojanović
,
N. Šternić
,
V. Kostic
Clinical neuropharmacology
1997
Corpus ID: 46187458
Hemiballism is a relatively rare hyperkinetic disorder; treatment is based mainly on neuroleptics and drugs that decrease release…
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1995
1995
Ephedrine-induced mania from an herbal diet supplement.
Capwell Rr
1995
Corpus ID: 221947736
1995
1995
Conversions from clozapine to other antipsychotic drugs.
R. Baldessarini
,
D. Gardner
,
D. Garver
Archives of General Psychiatry
1995
Corpus ID: 35579501
Conversions between dissimilar antipsychotic agents can be problematic. Agents of low potency present risks of central depressant…
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1993
1993
Low cerebrospinal fluid homovanillic acid-5-hydroxyindoleacetic acid ratio predicts clozapine efficacy: a replication.
S. Risch
,
R. Lewine
Archives of General Psychiatry
1993
Corpus ID: 315527
Pickar et al1reported the superior efficacy of clozapine over fluphenazine and placebo in eight (38%) of 21 neuroleptic treatment…
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1981
1981
Synthesis of clozapine analogues and their affinity for clozapine and spiroperidol binding sites in rat brain.
T. de Paulis
,
C. R. Betts
,
H. E. Smith
,
P. Mobley
,
D. Manier
,
F. Sulser
Journal of Medicinal Chemistry
1981
Corpus ID: 37119976
Analogues of clozapine, some prepared by a novel, shorter synthesis than those described previously, were evaluated as potential…
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1975
1975
An investigation of clozapine in the treatment of acute and chronic schizophrenia and gross behaviour disorders.
R. E. Hemphill
,
F. Pascoe
,
T. Zabow
South African medical journal = Suid-Afrikaanse…
1975
Corpus ID: 11421946
Fifty-two mental hospital cases of acute and chronic schizophrenia and gross behaviour disorders were investigated and observed…
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1970
1970
Das Neuroleptikum 100-129/HF-1854 (Clozapin) in der Psychiatrie
H. Gross
,
E. Langner
1970
Corpus ID: 148997052