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Clozapine

Known as: Clozapinum, Clozapin, 5H-Dibenzo(b,e)(1,4)diazepine, 8-chloro-11-(4-methyl-1-piperazinyl)- 
A tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays… 
National Institutes of Health

Related topics

Related topics

40 relations
Adrenergic alpha-Antagonists [MoA]Bipolar DisorderCYP1A2 protein, humanClozapine 100 MG Oral Tablet

Broader (6)

Antipsychotic AgentsBenzodiazepineBenzodiazepinesCarbamazepine

Narrower (8)

ClozarilJL 13 compoundJL 18Leponex

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Prevalence, utilization patterns, and predictors of antipsychotic polypharmacy: experience in a multistate Medicaid population, 1998-2003.
Highly Cited
2005
Highly Cited
2005
The SNAP-25 gene may be associated with clinical response and weight gain in antipsychotic treatment of schizophrenia
Highly Cited
2000
Highly Cited
2000
Simultaneous determination of the HIV protease inhibitors indinavir, amprenavir, saquinavir, ritonavir, nelfinavir and the non-nucleoside reverse transcriptase inhibitor efavirenz by high-performance…
Highly Cited
1996
Highly Cited
1996
A prospective 1–5 year outcome study in first‐admitted and readmitted schizophrenic patients; relationship to heredity, premorbid adjustment, duration of disease and education level at index…
Wieselgren, I‐M, Lindström LH. A prospective 1–5 year outcome study in first‐admitted and readmitted schizophrenic patients… 
Highly Cited
1994
Highly Cited
1994
Effects of typical and atypical neuroleptics on Fos protein expression in the rat forebrain
Highly Cited
1992
Highly Cited
1992
NNC-112, NNC-687 and NNC-756, new selective and highly potent dopamine D1 receptor antagonists.
Review
1989
Review
1989
Clozapine: an atypical antipsychotic agent.
The pharmacology, pharmacokinetics, clinical efficacy, adverse effects, dosage, and cost of the atypical antipsychotic drug… 
Highly Cited
1977
Highly Cited
1977
A comparison of pre- and postsynaptic effects of α-adrenolytic drugs in the pulmonary artery of the rabbit
Highly Cited
1977
Highly Cited
1977
Chronic phenylethylamine stereotypy in rats: a new animal model for schizophrenia?
Highly Cited
1976
Highly Cited
1976
The noradrenergic cyclic AMP generating system in the limbic forebrain: pharmacological characterization in vitro and possible role of limbic noradrenergic mechanisms in the mode of action of…
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