Leponex
National Institutes of Health
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BACKGROUND
Delirium occurs in up to 30% of hospitalised patients and is associated with prolonged hospital stay and increased…
Bifeprunox: a novel antipsychotic agent with partial agonist properties at dopamine D2 and serotonin 5-HT1A receptors
Granulocytopenia 1 is an established risk of treatment with tricyclic antipsychotic agents, including the phenothiazine group…
Clozapine is a piperazine-substituted tricyclic compound of the dibenzodiazepin group (Leponex ®, Sandoz AG). The drug is used to…
We describe an analytical procedure for the simultaneous quantification of citalopram (seropram), clozapine (leponex), fluoxetine…
A 67 year-old woman in steady-state treatment with clozapine 150 mg/24 h was co-medicated with 100 mg/24 h of fluvoxamine. During…
Two personally observed cases of severe agranulocytosis within 3 months, one of them fatal, could be attributed to the new…