Skip to search formSkip to main contentSkip to account menu

Clavulanic Acid

Known as: (2R,3Z,5R)-3-(2-HYDROXYETHYLIDENE)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, ácido clavulánico, 4-Oxa-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3-(2-hydroxyethylidene)-7-oxo-, (2R-(2alpha,3Z,5alpha)) 
A semisynthetic beta-lactamase inhibitor isolated from Streptomyces. Clavulanic acid contains a beta-lactam ring and binds strongly to beta-lactamase… 
National Institutes of Health

Related topics

Related topics

15 relations
Amoxicillin 250 MG / Clavulanate 125 MG Oral Tablet [Augmentin]Amoxicillin 875 MG / Clavulanate 125 MG Oral TabletClavulanate / TicarcillinIn Blood

Narrower (4)

BRL-14151ClavulanateClavulanic Acid, Monosodium Saltclavulanate potassium

Broader (2)

Clavulanic Acidsbeta-Lactamase Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Susceptibility of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis to 17 oral antimicrobial agents based on pharmacodynamic parameters: 1998-2001 U S Surveillance Study.
Highly Cited
2003
Highly Cited
2003
Efficacy and safety of azithromycin vs levofloxacin in the outpatient treatment of acute bacterial exacerbations of chronic bronchitis.
STUDY OBJECTIVES To compare the safety and efficacy of oral azithromycin and levofloxacin in the treatment of outpatients with… 
Highly Cited
2002
Highly Cited
2002
The clavulanic acid biosynthetic cluster of Streptomyces clavuligerus: genetic organization of the region upstream of the car gene.
The genetic organization of the region upstream of the car gene of the clavulanic acid biosynthetic gene cluster of Streptomyces… 
Highly Cited
1999
Highly Cited
1999
Natural antibiotic susceptibility of Escherichia coli, Shigella, E. vulneris, and E. hermannii strains.
Review
1997
Review
1997
A 1994-95 survey of Haemophilus influenzae susceptibility to ten orally administered agents. A 187 clinical laboratory center sample in the United States.
Review
1990
Review
1990
A descriptive study of 42 cases of Branhamella catarrhalis pneumonia.
Highly Cited
1990
Highly Cited
1990
Lack of influence of beta-lactamase-producing flora on recovery of group A streptococci after treatment of acute pharyngitis.
Review
1985
Review
1985
Contribution of beta-lactamases to bacterial resistance and mechanisms to inhibit beta-lactamases.
Highly Cited
1984
Highly Cited
1984
In vitro activity of ticarcillin plus clavulanic acid against 632 clinical isolates
A total of 632 clinical bacterial isolates were tested for susceptibility to twofold dilutions of ticarcillin alone and in… 
Highly Cited
1978
Highly Cited
1978
Chemical studies on the inactivation of Escherichia coli RTEM beta-lactamase by clavulanic acid.
Incubation of clavulanic acid with the beta-lactamase from Escherichia coli RTEM leads to enzyme-catalyzed depletion of… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)