Skip to search formSkip to main contentSkip to account menu

Chromosomal structural abnormalities

Known as: Chromosomal Rearrangement, Structural Chromosome Aberration, Structural Chromosomal Abnormality 
Any change in the structure of one or more chromosomes.
National Institutes of Health

Related topics

Related topics

9 relations
Acute Myeloid Leukemia with Recurrent Genetic AbnormalitiesAcute Promyelocytic LeukemiaCore Binding Factor Acute Myeloid LeukemiaCytogenetically Normal Acute Myeloid Leukemia

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Abstract 440: Quantification of somatic chromosomal rearrangements in circulating cell-free DNA from ovarian cancers
2003
2003
Mosaicism del(8p)/inv dup(8p) in a dysmorphic female infant: a mosaic formed by a meiotic error at the 8p OR gene and an independent terminal deletion event
Various chromosomal rearrangements are associated with the distal 8p region. Among them are the inv dup(8p),1 del(8p22),2–5 and… 
1998
1998
Analysis of large and small colony L5178Y tk-/- mouse lymphoma mutants by loss of heterozygosity (LOH) and by whole chromosome 11 painting: detection of recombination.
Analysis of 122 spontaneous large and small colony mutants derived from L5178Y tk +/- mouse lymphoma cells at 28 heteromorphic… 
1994
1994
Ambient air pollutants in upper Silesia: partial chemical composition and biological activity.
The air monitoring system in Upper Silesia has provided abundant data on airborne pollutants. Air quality in this region is bad… 
Highly Cited
1993
Highly Cited
1993
Frequent homozygous deletions in lung cancer cell lines detected by a DNA marker located at 3p21.3-p22.
Frequent allelic losses of chromosome 3p in lung cancer have been reported in a number of studies, and we previously demonstrated… 
Review
1991
Review
1991
p53 in the diagnosis of human neoplasia.
The traditional methods used to diagnose cancer and predict its course have been increasingly aided by molecular genetics. Unique… 
Highly Cited
1986
Highly Cited
1986
Site-specific chromosomal rearrangements induced in human diploid cells by x-irradiation.
A total of 130 stable, two-break reciprocal translocations were scored in G-banded karyotypes prepared from 375 metaphase spreads… 
1985
1985
Mechanisms of human cell neoplastic transformation: X-ray-induced abnormal clone formation in long-term cultures of human diploid fibroblasts.
Early passage cultures of a strain of normal human diploid fibroblasts were exposed to various doses of X-rays. The cells were… 
1981
1981
Genes in Neurospora that suppress recombination when they are heterozygous.
Genes that suppress recombination when heterozygous have been found distributed as a polymorphism in wild and laboratory… 
Highly Cited
1980
Highly Cited
1980
Ionizing radiation-induced 6-thioguanine-resistant clones in synchronous CHO cells.
When cultured Chinese hamster ovary (CHO) cells are exposed to acute doses of ionizing radiation at different times during the…