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Chromosomal structural abnormalities

Known as: Chromosomal Rearrangement, Structural Chromosome Aberration, Structural Chromosomal Abnormality 
Any change in the structure of one or more chromosomes.
National Institutes of Health

Related topics

Related topics

9 relations
Acute Myeloid Leukemia with Recurrent Genetic AbnormalitiesAcute Promyelocytic LeukemiaCore Binding Factor Acute Myeloid LeukemiaCytogenetically Normal Acute Myeloid Leukemia

Papers overview

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Highly Cited
2013
Highly Cited
2013
Crizotinib versus chemotherapy in advanced ALK-positive lung cancer.
BACKGROUND In single-group studies, chromosomal rearrangements of the anaplastic lymphoma kinase gene (ALK) have been associated… 
Highly Cited
2011
Highly Cited
2011
Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development
Highly Cited
2007
Highly Cited
2007
Mapping autism risk loci using genetic linkage and chromosomal rearrangements
Autism spectrum disorders (ASDs) are common, heritable neurodevelopmental conditions. The genetic architecture of ASDs is complex… 
Highly Cited
2005
Highly Cited
2005
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.
Highly Cited
2005
Highly Cited
2005
Initial sequence of the chimpanzee genome and comparison with the human genome
Here we present a draft genome sequence of the common chimpanzee (Pan troglodytes). Through comparison with the human genome, we… 
Highly Cited
2005
Highly Cited
2005
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
Recurrent chromosomal rearrangements have not been well characterized in common carcinomas. We used a bioinformatics approach to… 
Highly Cited
2001
Highly Cited
2001
Chromosomal rearrangements and speciation.
  • L. Rieseberg
  • Trends in ecology & evolution
  • 2001
  • Corpus ID: 2432487
Highly Cited
1996
Highly Cited
1996
AML1, the Target of Multiple Chromosomal Translocations in Human Leukemia, Is Essential for Normal Fetal Liver Hematopoiesis
Highly Cited
1996
Highly Cited
1996
Karyotyping human chromosomes by combinatorial multi-fluor FISH
We have developed epifluorescence filter sets and computer software for the detection and discrimination of 27 different DNA… 
Highly Cited
1992
Highly Cited
1992
Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
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