Acute Promyelocytic Leukemia

Known as: Leukemia, Progranulocytic, AML M3, LEUKEMIA, PROMYELOCYTIC 
An acute myeloid leukemia (AML) in which abnormal promyelocytes predominate. It is characterized by the t(15;17)(q22;q12) translocation. There are… (More)
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
BACKGROUND All-trans retinoic acid (ATRA) with chemotherapy is the standard of care for acute promyelocytic leukemia (APL… (More)
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Review
2001
Review
2001
All trans retinoic acid (ATRA) is able to induce complete remission (CR) in almost all patients with acute promyelocytic leukemia… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Two reports from China have suggested that arsenic trioxide can induce complete remissions in patients with acute… (More)
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Highly Cited
1997
Highly Cited
1997
The therapeutic effect of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL) was evaluated among 15… (More)
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Highly Cited
1997
Highly Cited
1997
The malignant cells of acute promyelocytic leukemia (APL) contain a reciprocal chromosomal translocation that fuses the… (More)
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Review
1993
Review
1993
Perhaps the most important advance in this field is not the specific actions of all-trans-retinoic acid in acute promyelocytic… (More)
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Highly Cited
1991
Highly Cited
1991
A unique mRNA produced in leukemic cells from a t(15;17) acute promyelocytic leukemia (APL) patient encodes a fusion protein… (More)
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Highly Cited
1991
Highly Cited
1991
Acute promyelocytic leukemia (APL) is a well-defined entity among acute leukemia, cytogenetically characterized by a t(15;17… (More)
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Highly Cited
1990
Highly Cited
1990
Twenty-two patients with acute promyelocytic leukemia were treated with all-trans retinoic acid (RA, 45 mg/m2 per day) for 90… (More)
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Highly Cited
1989
Highly Cited
1989
Twenty-four patients with acute promyelocytic leukemia (API) were treated with all-trans retinoic acid (45 to 100 mg/m2/day). Of… (More)
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