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Acute Promyelocytic Leukemia

Known as: Leukemia, Progranulocytic, AML M3, LEUKEMIA, PROMYELOCYTIC 
An acute myeloid leukemia (AML) in which abnormal promyelocytes predominate. It is characterized by the t(15;17)(q22;q12) translocation. There are… Expand
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Acute promyelocytic leukemia (APL) is a distinct subtype of acute myeloid leukemia. Morphologically, it is identified as the M3… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Two reports from China have suggested that arsenic trioxide can induce complete remissions in patients with acute… Expand
Highly Cited
1997
Highly Cited
1997
Resveratrol, a phytoalexin found in grapes and other food products, was purified and shown to have cancer chemopreventive… Expand
Highly Cited
1991
Highly Cited
1991
A unique mRNA produced in leukemic cells from a t(15;17) acute promyelocytic leukemia (APL) patient encodes a fusion protein… Expand
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Highly Cited
1991
Highly Cited
1991
We have previously shown that the t(15;17) translocation specifically associated with acute promyelocytic leukemia (APL) fuses… Expand
Highly Cited
1991
Highly Cited
1991
BACKGROUND AND METHODS Patients with acute promyelocytic leukemia have a characteristic (15;17) translocation, with a breakpoint… Expand
Highly Cited
1990
Highly Cited
1990
Twenty-two patients with acute promyelocytic leukemia were treated with all-trans retinoic acid (RA, 45 mg/m2 per day) for 90… Expand
Highly Cited
1989
Highly Cited
1989
Twenty-four patients with acute promyelocytic leukemia (APL) were treated with all-trans retinoic acid (45 to 100 mg/m2/day). Of… Expand
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Review
1987
Review
1987
The HL-60 cell line, derived from a single patient with acute promyelocytic leukemia, provides a unique in vitro model system for… Expand
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Highly Cited
1978
Highly Cited
1978
A human leukemic cell line (designated HL-60) has recently been established from the peripheral blood leukocytes of a patient… Expand