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Cholinesterase Inhibitors

Known as: Anti-Cholinesterases, Inhibitors, Cholinesterase, anti cholinesterase 
Drugs that inhibit cholinesterases. The neurotransmitter ACETYLCHOLINE is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. When… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Dementias have become a major public health concern because of their increasing prevalence, chronicity, caregiver burden, and… Expand
Review
2006
Review
2006
  • J. Birks
  • The Cochrane database of systematic reviews
  • 2006
  • Corpus ID: 6068786
BACKGROUND Since the introduction of the first cholinesterase inhibitor (ChEI) in 1997, most clinicians and probably most… Expand
Review
2005
Review
2005
The dementia with Lewy bodies (DLB) Consortium has revised criteria for the clinical and pathologic diagnosis of DLB… Expand
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Review
2005
Review
2005
Abstract Objectives Pharmacological treatment of Alzheimer's disease focuses on correcting the cholinergic deficiency in the… Expand
Review
2004
Review
2004
An important aspect of brain cholinesterase function is related to enzymatic differences. The brain of mammals contains two major… Expand
Review
2003
Review
2003
CONTEXT Cholinesterase inhibitors are the primary treatment for the cognitive symptoms of Alzheimer disease (AD). Cholinergic… Expand
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Review
1998
Review
1998
  • S. Stahl
  • Hospital practice
  • 1998
  • Corpus ID: 31422677
New cholinesterase inhibitors capable of slowing the progression of Alzheimer's disease are being introduced at a rapid pace. In… Expand
Highly Cited
1994
Highly Cited
1994
  • K. Davis
  • Neuropsychopharmacology
  • 1994
  • Corpus ID: 5977401
Data generated to date by a number of large studies (Eagger et al, Davis et al, Farlow et al, and Murphy et al) indicate that… Expand
Highly Cited
1986
Highly Cited
1986
We treated 17 patients who had moderate to severe Alzheimer's disease with oral tetrahydroaminoacridine (THA), a centrally active… Expand
Highly Cited
1974
Highly Cited
1974
The relationship of the cholinergic system of the brain to memory and cognitive functions was studied in human subjects by the… Expand