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Chitin Biochemistry: Synthesis, Hydrolysis and Inhibition
TLDR
Chitin research carries practical aspect as the physiologically crucial synthesis and hydrolysis of the polymer have been regarded as suitable, attractive and largely selective targets for interference and for producing effective pharmaceuticals and safe biopesticides. Expand
Chitin Biochemistry: Synthesis and Inhibition
TLDR
Synthesis of chitin involves concerted multifaceted cellular activities starting from biotrans­ formations of simple metabolites and culminating in the emergence of a polymer to be extruded outside cell membranes. Expand
A point mutation in the ethylene-inducing xylanase elicitor inhibits the beta-1-4-endoxylanase activity but not the elicitation activity.
TLDR
The data show that the xylanase activity of EIX elicitor can be separated from the elicitation process, as some of the mutants lack the former but retain the latter. Expand
Chitin synthesis and inhibition: a revisit.
  • E. Cohen
  • Biology, Medicine
  • Pest management science
  • 1 October 2001
TLDR
The recent isolation and sequencing of insect CS genes should help in elucidating various aspects of chitin biochemistry and inhibition, and are expected to shed light on the mode of action of acylurea insecticides. Expand
Inhibition of Tribolium gut chitin synthetase.
TLDR
These studies and preliminary findings on an integumental enzyme indicate that CS of these tissues is not sensitive to the direct action of benzoylphenyl ureas, which leads to speculation that the Benzoyl Phenyl Ureas act either as CS inhibitors via active metabolites formed in the integument or as blocking agents by direct binding to non-CS sites important in chitin polymerization and fibrillogenesis. Expand
Cytotoxicity of nimbolide, epoxyazadiradione and other limonoids from neem insecticide.
Neem seed preparations contain not only azadirachtin as the active insect antifeedant or growth regulator but also a variety of their limonoids, some of which are cytotoxic to N1E-115 neuroblastomaExpand
Pesticide-mediated homeostatic modulation in arthropods
TLDR
Pesticide-induced homeostatic modulation (PIHM) is suggested as a broader term to include both hormesis and stimulatory effects of pesticides on non-target pests as well as biological, chemical, and/or photochemical modifications. Expand
Accumulation of Secondary Carotenoids in Chlorella zofingiensis
TLDR
It is suggested that secondary carotenoids have a photo-protective role, that is, under high light conditions they protect chlorophyll and other photosynthetic pigments against damage. Expand
Chitin synthesis and degradation as targets for pesticide action.
  • E. Cohen
  • Biology, Medicine
  • Archives of insect biochemistry and physiology
  • 1993
TLDR
Hydrolytic degradation of the chitin polymer is essential for hyphal growth, branching, and septum formation in fungal systems as well as for the normal molting of arthropods. Expand
Properties of Tribolium gut chitin synthetase
TLDR
The polymerization product formed by the Tribolium enzyme is stable in alkali but hydrolyzed by chitinase, and its activation and inhibition properties are similar to those of fungal CS. Expand
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