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Choline Kinase

Known as: Choline Phosphokinase, ATP:choline phosphotransferase, Choline Kinase [Chemical/Ingredient] 
An enzyme that is active in the first step of choline phosphoglyceride (lecithin) biosynthesis by catalyzing the phosphorylation of choline to… 
National Institutes of Health

Related topics

Related topics

13 relations
CHKA geneCHKB geneCHPT1 geneIn Blood

Narrower (2)

CHKA protein, humanCHKA wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Arabidopsis CHOLINE/ETHANOLAMINE KINASE 1 (CEK1) is a primary choline kinase localized at the ER and involved in ER stress tolerance.
Choline kinase catalyzes the initial reaction step of choline metabolism that produces phosphocholine, a prerequisite for the… 
2015
2015
Choline kinase‐α protein and phosphatidylcholine but not phosphocholine are required for breast cancer cell survival
High levels of total choline and phosphocholine (PC) are consistently observed in aggressive cancers. Choline kinase (Chk… 
Highly Cited
2010
Highly Cited
2010
Cancer esearch rated Systems and Technologies timodal Mass Spectrometric Imaging of Small Molecules eals Distinct Spatio-Molecular Signatures in R erentially Metastatic Breast Tumor Models
Downlo sphocholine (PC) and total choline (tCho) are increased in malignant breast tumors. In this study, we ned magnetic… 
Highly Cited
1998
Highly Cited
1998
Phospholipid‐Metabolizing Enzymes in Alzheimer's Disease: Increased Lysophospholipid Acyltransferase Activity and Decreased Phospholipase A2 Activity
Abstract: Damage to brain membrane phospholipids may play an important role in the pathogenesis of Alzheimer's disease (AD… 
1986
1986
Choline kinase II is present only in nodules that synthesize stable peribacteroid membranes.
Host-cell cytoplasm from soybean plants infected with the peribacteroid membrane (PBM)-building Rhizobium japonicum strain 61-A… 
1986
1986
Comparison of the enzyme activities of phosphatidylcholine, phosphatidylglycerol and phosphatidylinositol synthesis in freshly isolated type II pneumocytes and whole lung from the adult rat.
Highly Cited
1980
Highly Cited
1980
Regulation of phosphatidylcholine biosynthesis in cultured chick embryonic muscle treated with phospholipase C.
1977
1977
Choline kinase and ethanolamine kinase are separate, soluble enzymes in rat liver.
Choline kinase and ethanolamine kinase are located in the cytosol from rat liver and have been copurified more than 500-fold by… 
Highly Cited
1977
Highly Cited
1977
Alteration of central cholinergic function by chronic lead acetate exposure.
1972
1972
Fluorometric enzyme assay for choline and acetylcholine.
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