CHKA protein, human

Known as: CKI, CHOK, Choline Kinase Alpha 
Choline kinase alpha (457 aa, ~52 kDa) is encoded by the human CHKA gene. This protein plays a role in phospholipid biosynthesis.
National Institutes of Health

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Highly Cited
2006
Highly Cited
2006
p27kip1, a cyclin-dependent kinase (CDK) inhibitor (CKI), generally suppresses CDK activity in proliferating cells. Although… (More)
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Highly Cited
2003
Highly Cited
2003
Wnt signaling causes changes in gene transcription that are pivotal for normal and malignant development. A key effector of the… (More)
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Highly Cited
2002
Highly Cited
2002
␤-catenin protein level and Wnt signaling. and S45) at the amino-terminal region of ␤-catenin (Figure 1A) are conserved from… (More)
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Highly Cited
2002
Highly Cited
2002
Recent studies have shown that casein kinase I epsilon (CKIepsilon) is an essential regulator of the mammalian circadian clock… (More)
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Highly Cited
2002
Highly Cited
2002
Dapper was isolated in a screen for proteins interacting with Dishevelled, a key factor in Wnt signaling. Dapper and Dishevelled… (More)
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Highly Cited
2001
Highly Cited
2001
UNLABELLED Elevated levels of choline (trimethyl-2-hydroxyethylammonium) and choline kinase (CK) activity in neoplasms have… (More)
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Highly Cited
1999
Highly Cited
1999
Cyclin E-Cdk2 kinase activation is an essential step in Myc-induced proliferation. It is presumed that this requires… (More)
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Highly Cited
1998
Highly Cited
1998
Arterial lesions in cardiovascular diseases are characterized by proliferation and migration of smooth muscle cells as well as… (More)
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Highly Cited
1998
Highly Cited
1998
Damage to brain membrane phospholipids may play an important role in the pathogenesis of Alzheimer's disease (AD); however, the… (More)
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Highly Cited
1997
Highly Cited
1997
Cyclin-dependent kinase inhibitors (CKIs) play key roles in controlling the eukaryotic cell cycle by coordinating cell… (More)
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