Skip to search formSkip to main contentSkip to account menu

Cholestasis

Known as: bile obstruction, obstruction bile duct, bile ducts obstructions 
Any condition in which the release of bile from the liver is blocked. The blockage can occur in the liver (intrahepatic cholestasis) or in the bile… 
National Institutes of Health

Related topics

Related topics

45 relations

Narrower (12)

Alagille SyndromeArthrogryposis renal dysfunction cholestasis syndromeBile acid synthesis defect, congenital, 1Biliary Atresia
Alagille Syndrome 1Combined Oxidative Phosphorylation Deficiency 1Diabetes Mellitus, Neonatal, with Congenital HypothyroidismDonohue Syndrome

Broader (1)

Biliary Tract Diseases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Molecular pathogenesis of cholestasis.
The formation of bile is a vital function, and its impairment by drugs or infectious, autoimmune, metabolic, or genetic disorders… 
Review
2012
Review
2012
Chronic obstructive pulmonary disease
Highly Cited
2010
Highly Cited
2010
Comparison of shunt types in the Norwood procedure for single-ventricle lesions.
BACKGROUND The Norwood procedure with a modified Blalock-Taussig (MBT) shunt, the first palliative stage for single-ventricle… 
Highly Cited
2009
Highly Cited
2009
Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver
An important function of hepatocytes is the biotransformation and elimination of various drugs, many of which are organic cations… 
Review
2006
Review
2006
Hepatobiliary transporters and drug‐induced cholestasis
Drug‐induced liver injury is an important clinical problem with significant morbidity and mortality. Whereas for most… 
Highly Cited
2004
Highly Cited
2004
Mutations in VPS33B, encoding a regulator of SNARE-dependent membrane fusion, cause arthrogryposis–renal dysfunction–cholestasis (ARC) syndrome
ARC syndrome (OMIM 208085) is an autosomal recessive multisystem disorder characterized by neurogenic arthrogryposis multiplex… 
Highly Cited
2003
Highly Cited
2003
Neutrophils aggravate acute liver injury during obstructive cholestasis in bile duct–ligated mice
Obstruction of the common bile duct in a variety of clinical settings leads to cholestatic liver injury. An important aspect of… 
Highly Cited
2000
Highly Cited
2000
Liver from bone marrow in humans
It has been shown in animal models that hepatocytes and cholangiocytes can derive from bone marrow cells. We have investigated… 
Highly Cited
1987
Highly Cited
1987
Description and Rationale of a New Operation for Chronic Pancreatitis
An operation is described that is useful in the management of patients with chronic pancreatitis and its complications. The… 
Highly Cited
1971
Highly Cited
1971
Etiologic factors in 1294 consecutive cases of male infertility.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)