Alagille Syndrome

Known as: Syndrome, Watson Alagille, Hepatic Ductular Hypoplasia, Syndromatic, Dysplasia, Arteriohepatic 
A multisystem disorder that is characterized by aplasia of intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC), and malformations in the… (More)

Topic mentions per year

Topic mentions per year

1965-2017
05019652017

Papers overview

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2012
2012
BACKGROUND Alagille syndrome (ALGS) is a dominant, multisystem disorder caused by mutations in the Jagged1 (JAG1) ligand in 94… (More)
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2006
Highly Cited
2006
Alagille syndrome (AGS) is caused by mutations in the gene for the Notch signaling pathway ligand Jagged1 (JAG1), which are found… (More)
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2006
2006
Alagille syndrome (AGS) is caused by heterozygous mutations in JAG1, and mutations have been previously reported in about 70% of… (More)
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Highly Cited
2002
Highly Cited
2002
Alagille syndrome is a human autosomal dominant developmental disorder characterized by liver, heart, eye, skeletal, craniofacial… (More)
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Highly Cited
1999
Highly Cited
1999
We have studied 92 patients with Alagille syndrome (AGS) to determine the frequency of clinical manifestations and to correlate… (More)
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Highly Cited
1999
Highly Cited
1999
The Notch signaling pathway is an evolutionarily conserved intercellular signaling mechanism essential for embryonic development… (More)
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1999
1999
OBJECTIVE To assess the type and frequency of ocular abnormalities occurring in Alagille syndrome (AS) in a large group of… (More)
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1999
1999
BACKGROUNDS & AIMS Mutations in the JAGGED1 gene are responsible for the Alagille syndrome, an autosomal dominant disorder… (More)
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1997
Highly Cited
1997
Alagille syndrome is an autosomal dominant disorder characterized by abnormal development of liver, heart, skeleton, eye, face… (More)
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Highly Cited
1997
Highly Cited
1997
Alagille syndrome (AGS) is an autosomal-dominant disorder characterized by intrahepatic cholestasis and abnormalities of heart… (More)
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