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Distinct morphogenetic functions of similar small GTPases: Drosophila Drac1 is involved in axonal outgrowth and myoblast fusion.
Cloned Drosophila homologs of rac and CDC42, Drac1, and Dcdc42 proteins cause qualitatively distinct morphological defects, suggesting that similar GTPases in the same subfamily have unique roles in morphogenesis.
Changing subunit composition of heteromeric NMDA receptors during development of rat cortex
Direct evidence is presented that NMDA receptors exist in rat neocortex as heteromeric complexes of considerable heterogeneity, some containing both NR2A and NR2B subunits.
Properties of the larval neuromuscular junction in Drosophila melanogaster.
  • L. Jan, Y. Jan
  • Chemistry, Medicine
    The Journal of physiology
  • 1 October 1976
The anatomy and physiology of the Drosophila larval neuromuscular junction were studied and Mg2+ reduces transmitter release without altering the fourth power dependence on [Ca2+]o.
Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases
Functional and biochemical evidence is presented that cell-surface clustering of Shaker-subfamily K+ channels is mediated by the PSD-95 family of membrane-associated putative guanylate kinases, and the ability of PDZ domains to function as independent modules for protein–protein interaction, and their presence in other junction-associated molecules suggest that PDZ-domain-containing polypeptides may be widely involved in the organization of proteins at sites of membrane specialization.
Tiling of the Drosophila epidermis by multidendritic sensory neurons.
Together, the data suggest that widespread tiling of the larval body wall involves interactions between growing dendritic processes and as yet unidentified signals that allow avoidance by like dendrites.