Ceramidase

Known as: N-Acylsphingosine Amidohydrolase, Ceramidases [Chemical/Ingredient], Ceramidases 
Amidohydrolases that are specific for the cleavage of the N-acyl linkage of CERAMIDES. Ceramidases are classified as acidic, neutral or basic… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Gaucher disease is a rare inborn error of glycosphingolipid metabolism due to deficiency of lysosomal acid β-glucocerebrosidase… (More)
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Highly Cited
2010
Highly Cited
2010
Abnormal sphingolipid metabolism has been previously reported in Alzheimer's disease (AD). To extend these findings, several… (More)
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Highly Cited
2008
Highly Cited
2008
Microbial lung infections are the major cause of morbidity and mortality in the hereditary metabolic disorder cystic fibrosis… (More)
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2006
2006
Complex sphingolipids are abundant as eukaryotic cell membrane components, whereas their metabolites, in particular ceramide… (More)
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Highly Cited
2005
Highly Cited
2005
Bioactive N-acylethanolamines, including anandamide (an endocannabinoid) and N-palmitoylethanolamine (an anti-inflammatory and… (More)
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2004
2004
A screen for Drosophila synaptic dysfunction mutants identified slug-a-bed (slab). The slab gene encodes ceramidase, a central… (More)
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2001
2001
The biosynthesis of human acid ceramidase (hAC) starts with the expression of a single precursor polypeptide of approximately 53… (More)
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Highly Cited
1999
Highly Cited
1999
Oxidized LDL (oxLDL) have been implicated in diverse biological events leading to the development of atherosclerotic lesions. We… (More)
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Highly Cited
1997
Highly Cited
1997
Ceramide (N-acylsphingosine) biosynthesis has been proposed to involve introduction of the 4,5-trans-double bond of sphingosine… (More)
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Highly Cited
1966
Highly Cited
1966
The accumulation of abnormal quantities of glucocerebroside in the reticuloendothelial cells of patients with Gaucher's disease… (More)
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