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Acid Ceramidase

Known as: AC, Acid Ceramidase [Chemical/Ingredient], Acylsphingosine Deacylase 
A ceramidase subtype that is active at acid pH. It plays an important role in sphingolipid degradation by catalyzing the lysosomal hydrolysis of… 
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Acid ceramidase (ACDase) deficiency is a spectrum of disorders that includes a rare lysosomal storage disorder called Farber… 
Highly Cited
2016
Highly Cited
2016
Glycosphingoid bases are elevated in inherited lysosomal storage disorders with deficient activity of glycosphingolipid… 
Highly Cited
2015
Highly Cited
2015
Bioactive sphingolipids including ceramides are involved in a variety of pathophysiological processes by regulating cell death… 
Highly Cited
2012
Highly Cited
2012
Review
2010
Review
2010
  • H. Hama
  • Biochimica et biophysica acta
  • 2010
  • Corpus ID: 25477860
Review
2006
Review
2006
Highly Cited
2005
Highly Cited
2005
Recent studies indicate that insulin resistance and type 2 diabetes result from the accumulation of lipids in tissues not suited… 
Highly Cited
2003
Highly Cited
2003
Human acid ceramidase was overexpressed in Chinese hamster ovary cells by amplification of the transfected, full-length cDNA. The… 
Highly Cited
2000
Highly Cited
2000
The human acid ceramidase gene, that causes Farber disease, is located in 8p22, a region frequently altered in several cancers… 
Highly Cited
1995
Highly Cited
1995
Acid ceramidase (N-acylsphingosine deacylase, EC 3.5.1.23) is the lysosomal enzyme catalyzing the hydrolysis of ceramide to…