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Acid Ceramidase
Known as:
AC
, Acid Ceramidase [Chemical/Ingredient]
, Acylsphingosine Deacylase
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A ceramidase subtype that is active at acid pH. It plays an important role in sphingolipid degradation by catalyzing the lysosomal hydrolysis of…
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National Institutes of Health
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Related topics
Related topics
19 relations
ASAH1 gene
Alkaline Ceramidase 2
Cavity of lysosome
Ceramidase
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Development of an acid ceramidase activity-based probe.
Cécile M J Ouairy
,
M. Ferraz
,
+7 authors
H. Overkleeft
Chemical Communications
2015
Corpus ID: 9863340
Acid ceramidase is responsible for the ultimate step in the catabolism of (glyco)sphingolipids by hydrolysis of ceramide into…
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2014
2014
Targeting (cellular) lysosomal acid ceramidase by B13: design, synthesis and evaluation of novel DMG-B13 ester prodrugs.
A. Bai
,
Z. Szulc
,
+12 authors
A. Bielawska
Bioorganic & Medicinal Chemistry
2014
Corpus ID: 22574658
2011
2011
Clinical Utility of Serum Autoantibodies Detected by Protein Microarray in Melanoma
M. Sabel
,
Yashu Liu
,
K. Griffith
,
Jintang He
,
X. Xie
,
D. Lubman
International Journal of Proteomics
2011
Corpus ID: 16156049
Better prognostic and predictive markers in melanoma are needed to select patients for therapy. We utilized a dual-lectin…
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2008
2008
Population Genetic Analysis of the N-Acylsphingosine Amidohydrolase Gene Associated With Mental Activity in Humans
Hie-Lim Kim
,
Y. Satta
Genetics
2008
Corpus ID: 24767675
To understand the evolution of human mental activity, we performed population genetic analyses of nucleotide sequences (∼11 kb…
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2007
2007
Overexpression and mass spectrometry analysis of mature human acid ceramidase
H. Schulze
,
U. Schepers
,
K. Sandhoff
Biological chemistry
2007
Corpus ID: 12612022
Abstract Human acid ceramidase catalyzes the last step of lysosomal sphingolipid degradation, the hydrolysis of ceramide to…
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1997
1997
Model SV40-transformed fibroblast lines for metabolic studies of human prosaposin and acid ceramidase deficiencies.
M. Chatelut
,
K. Harzer
,
+9 authors
T. Levade
Clinica chimica acta; international journal of…
1997
Corpus ID: 7631219
1987
1987
Farber's disease (lysosomal acid ceramidase deficiency).
R. Jameson
,
P. Holt
,
J. Keen
Annals of the Rheumatic Diseases
1987
Corpus ID: 45741941
The patient presented with progressive joint deformity, a hoarse voice, subsequent cachexia, and myoclonic seizures. She was…
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Highly Cited
1986
Highly Cited
1986
Acid and alkaline ceramidases of rat tissues.
M. W. Spence
,
S. Beed
,
H. W. Cook
Biochemistry and cell biology = Biochimie et…
1986
Corpus ID: 6788211
Ceramidase (N-acylsphingosine deacylase) was measured in rat tissue homogenates with N-[1-14C]oleoyl- and N-[9,10-3H]palmitoyl…
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1981
1981
Role of lysosomal acid ceramidase in the metabolism of ceramide in human skin fibroblasts.
W. Chen
,
A. Moser
,
H. Moser
Archives of Biochemistry and Biophysics
1981
Corpus ID: 5574741
1976
1976
Diagnosis of lipogranulomatosis (Farber disease) by use of cultured fibroblasts.
J. Dulaney
,
A. Milunsky
,
J. Sidbury
,
N. Hobolth
,
H. Moser
Jornal de Pediatria
1976
Corpus ID: 28479058
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