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Cell Cycle Checkpoint Protein RAD17

Known as: RF-C/Activator 1 Homolog, hRad17 
Cell cycle checkpoint protein RAD17 (681 aa, ~77 kDa) is encoded by the human RAD17 gene. This protein is involved in the mediation of both cell… 
National Institutes of Health

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Cell Cycle CheckpointsCell Cycle ControlDNA RepairGenes, Regulator

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
A Conserved Physical and Functional Interaction between the Cell Cycle Checkpoint Clamp Loader and DNA Ligase I of Eukaryotes*
DNA ligase I joins Okazaki fragments during DNA replication and completes certain excision repair pathways. The participation of… 
2003
2003
Expression of mammalian paralogues of HRAD9 and Mrad9 checkpoint control genes in normal and cancerous testicular tissue.
Human and mouse paralogues of the evolutionarily conserved mammalian HRAD9 and Mrad9 cell cycle checkpoint control genes have… 
2001
2001
Overexpression of Hrad17 gene in non-small cell lung cancers correlated with lymph node metastasis.
2001
2001
Overexpression of HRad17 mRNA in human breast cancer: correlation with lymph node metastasis.
PURPOSE A novel human gene, designated HRad17, was identified as the human homologue of the Rad17 of Schizosaccharomyces pombe… 
Highly Cited
1999
Highly Cited
1999
HRad17, a human homologue of the Schizosaccharomyces pombe checkpoint gene rad17, is overexpressed in colon carcinoma.
Using the palindromic PCR-cDNA display method, we have cloned a novel gene overexpressed by human colon carcinoma relative to… 
1999
1999
Human and mouse RAD17 genes: identification, localization, genomic structure and histological expression pattern in normal testis and seminoma
Recently, the human orthologue to the cell cycle checkpoint genes rad17 (Schizosaccharomyces pombe) and RAD24 (Saccharomyces… 
1999
1999
hRAD17, a structural homolog of the Schizosaccharomyces pombe RAD17 cell cycle checkpoint gene, stimulates p53 accumulation
The RAD17 gene product of S. Pombe is an essential component of the checkpoint control pathway which responds to both DNA damage… 
1999
1999
Identification of a human homologue of the Schizosaccharomyces pombe rad17(+) checkpoint gene. (vol 273, pg 18340, 1998)
Highly Cited
1998
Highly Cited
1998
Identification of a Human Homologue of theSchizosaccharomyces pombe rad17 + Checkpoint Gene*
In the fission yeast Schizosaccharomyces pombe the rad17 + gene is required for both the DNA damage-dependent and the DNA… 
1998
1998
The mammalian Rad24 homologous to yeast Saccharomyces cerevisiae Rad24 and Schizosaccharomyces pombe Rad17 is involved in DNA damage checkpoint.
Cell cycle checkpoint proteins play critical roles in maintaining genomic stability and integrity to prevent the development of… 
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