Cell Cycle Checkpoint Protein RAD17

Known as: RF-C/Activator 1 Homolog, hRad17 
Cell cycle checkpoint protein RAD17 (681 aa, ~77 kDa) is encoded by the human RAD17 gene. This protein is involved in the mediation of both cell… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2011
01219982011

Papers overview

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2005
2005
In response to DNA damage or replication stress, the protein kinase ATR is activated and subsequently transduces genotoxic… (More)
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2004
2004
Telomere maintenance is essential for continued cell proliferation. Although most cells accomplish this by activating telomerase… (More)
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2004
2004
Human Rad17 (hRad17) is centrally involved in the activation of cell-cycle checkpoints by genotoxic agents or replication stress… (More)
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2003
2003
The checkpoint Rad proteins Rad17, Rad9, Rad1, Hus1, ATR, and ATRIP become associated with chromatin in response to DNA damage… (More)
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2002
2002
Human checkpoint Rad proteins are thought to function as damage sensors in the DNA damage checkpoint response pathway. The… (More)
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Highly Cited
2001
Highly Cited
2001
Genotoxic stress triggers the activation of checkpoints that delay cell-cycle progression to allow for DNA repair. Studies in… (More)
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2001
2001
ATR [ataxia-telangiectasia-mutated (ATM)- and Rad3-related] is a protein kinase required for both DNA damage-induced cell cycle… (More)
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2000
2000
DNA damage activates cell cycle checkpoints that prevent progression through the cell cycle. In yeast, the DNA damage checkpoint… (More)
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Highly Cited
1999
Highly Cited
1999
DNA damage activates cell cycle checkpoints in yeast and human cells. In the yeasts Saccharomyces cerevisiae and… (More)
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1999
1999
Using the palindromic PCR-cDNA display method, we have cloned a novel gene overexpressed by human colon carcinoma relative to… (More)
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