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Carcinogenic Nitrosourea

Any of several chemically related nitrosourea-derivates that increases the risk of human cancer and are highly lipid-soluble and act by alkylation… 
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
Intragastric formation and modulation of N-nitrosodimethylamine in a dynamic in vitro gastrointestinal model under human physiological conditions.
1992
1992
Sulfotransferase-mediated DNA binding of N-hydroxyarylamines(amide) in liver cytosols from human and experimental animals.
Characteristics of cytosolic sulfotransferase-mediated binding of carcinogenic N-hydroxyarylamines(amide) have been investigated… 
1989
1989
INVOLVEMENT OF MICROSOMAL CYTOCHROME P-450 IN THE MUTAGENIC ACTIVATION OF 9 CARCINOGENIC N-NITROSOPROPYLAMINE DERIVATIVES BY LIVER S9 FROM 5 ANIMAL SPECIES AND MAN
1986
1986
A comparative study of the mutagenic activation of N-nitrosopropylamines by various animal species and man: evidence for a cytochrome P-450 dependent reaction.
The mutagenic potential of seven carcinogenic N-nitrosopropylamines was examined by means of Ames' preincubation assay using… 
1985
1985
Mutagenic activation of carcinogenic N-nitrosopropylamines by rat liver: evidence for a cytochrome P-450 dependent reaction.
Mutagenic potential of carcinogenic N-nitrosopropylamines was examined by the Ames's liquid incubation assay, using rat liver… 
1981
1981
[Nitrosatable drugs (author's transl)].
Out of 61 drugs, considered to be potentially nitrosatable on the basis of their chemical structure and being used for oral… 
1964
1964
E-8-3 Concerning the Highly Carcinogenic F-Norsteranthrene(Steroids)
1963
1963
Part III. Chemistry, host entry, and metabolic fate of carcinogens
The skin, respiratory tract, and gastrointestinal tract are the organ systems through which environmental carcinogenic agents… 
1962
1962
Prevention by Cysteamine of the Inhibitory Effect of Carcinogenic N-Nitrosodialkylamines on Incorporation of Amino-Acids in Rat Liver
Prevention by Cysteamine of the Inhibitory Effect of Carcinogenic N-Nitrosodialkylamines on Incorporation of Amino-Acids in Rat… 
1958
1958
Effect of Diphosphopyridine Nucleotide on the Inhibition of Rat Liver 3-Hydroxy-anthranilic-Acid Oxidase by 2-Acetyl-aminofluorene and N-2-Fluorenyl-diacetamide
DUNNING et al.1 demonstrated that bladder cancer due to 2-acetylaminofluorene was produced in almost all rats (strain Fisher 344… 
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