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Increase of proton electrochemical potential and ATP synthesis in rat liver mitochondria irradiated in vitro by helium‐neon laser
Mitochondria Laser Transmembrane proton gradient Membrane potential ATP synthesis Oxygen uptake
Age‐dependent decline in the cytochrome c oxidase activity in rat heart mitochondria: role of cardiolipin
It is demonstrated that the lower cytochrome c oxidase activity in heart mitochondria from aged rats can be fully restored to the level of young control rats by exogenously added cardiolipin. Expand
Increase in RNA and protein synthesis by mitochondria irradiated with helium-neon laser.
Electrophoretic analysis made of the synthesis products clearly shows that He-Ne laser irradiation stimulates the synthesis of all mitochondrial transcription and translation products. Expand
Peroxidative damage to cardiac mitochondria: cytochrome oxidase and cardiolipin alterations
A close correlation between oxidative damage to cardiolipin and alterations in the cytochrome oxidase activity is established and may prove useful in probing molecular mechanism of free radicals induced peroxidative damage of mitochondria which has been proposed to contribute to aging and to chronic degenerative diseases. Expand
Myelin basic protein interaction with zinc and phosphate: fluorescence studies on the water-soluble form of the protein.
Anisotropy decay experiments demonstrated that these effects are due to the formation of MBP molecules into large aggregates and a possible physiological role for such interaction is discussed. Expand
Fatty-Acid Biosynthesis
The results indicate that microsomes are much more active than mitochondria in elongating and/ or desaturating fatty acids synthesized by cytoplasmic system, and evidence has been obtained that acyl groups are elongated and/or esterified into complex lipids as acyl-CoA and not as acy-ACP. Expand
The transport of sulphate and sulphite in rat liver mitochondria.
It is concluded that both sulphite and sulphate may be transported by the dicarboxylate carrier of rat liver mitochondria and also that sulphite may permeate by an additional mechanism; the latter may involve the permeation of sulphurous acid or SO(2) or an exchange of the sulphite anion for hydroxyl ion(s). Expand
Lipid Composition in Synaptic and Nonsynaptic Mitochondria from Rat Brains and Effect of Aging
Both cholesterol and phospholipid contents were found to be significantly different in synaptic compared to nonsynaptic mitochondria in rat brains and the effect of aging was studied. Expand
Control of succinate oxidation by succinate-uptake by rat-liver mitochondria.
The rate of respiration with succinate plus rotenone as substrate is controlled by succinate uptake, and citrate and other substrate anions are shown to be competitive with succinates with respect to both the oxidation and the uptake of succinate. Expand
A kinetic study of sulphate transport in rat liver mitochondria.
It is considered that sulphate and malonate probably bind to the same locus on the carrier, whereas phosphate occupies a different site, and the possible implications of this conclusion are discussed. Expand