Caloric Restriction

Known as: Restriction, Caloric 
Reduction in caloric intake without reduction in adequate nutrition. In experimental animals, caloric restriction has been shown to extend lifespan… (More)

Topic mentions per year

Topic mentions per year

1946-2017
010020019462016

Papers overview

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Highly Cited
2010
Highly Cited
2010
Caloric restriction (CR) extends the life span and health span of a variety of species and slows the progression of age-related… (More)
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Highly Cited
2009
Highly Cited
2009
Caloric restriction (CR), without malnutrition, delays aging and extends life span in diverse species; however, its effect on… (More)
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Highly Cited
2009
Highly Cited
2009
Animal studies suggest that diets low in calories and rich in unsaturated fatty acids (UFA) are beneficial for cognitive function… (More)
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Highly Cited
2008
Highly Cited
2008
The yeast sir2 gene and its orthologues in Drosophila and C. elegans have well-established roles in lifespan determination and… (More)
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Highly Cited
2007
Highly Cited
2007
The sirtuin family of nicotinamide adenine dinucleotide-dependent (NAD) deacetylases plays an important role in aging and… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Caloric restriction without malnutrition extends life span in a range of organisms including insects and mammals and… (More)
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Highly Cited
2004
Highly Cited
2004
Caloric restriction extends lifespan in numerous species. In the budding yeast Saccharomyces cerevisiae this effect requires Sir2… (More)
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Highly Cited
2004
Highly Cited
2004
A major cause of aging is thought to result from the cumulative effects of cell loss over time. In yeast, caloric restriction (CR… (More)
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Highly Cited
1999
Highly Cited
1999
The gene expression profile of the aging process was analyzed in skeletal muscle of mice. Use of high-density oligonucleotide… (More)
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Highly Cited
1998
Highly Cited
1998
Low caloric intake (caloric restriction) can lengthen the life span of a wide range of animals and possibly even of humans. To… (More)
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