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Pituitary-ovarian responses to nafarelin testing in the polycystic ovary syndrome.
It is concluded that women with polycystic ovary syndrome have masculinized pituitary and ovarian responses to stimulation by nafarelin, and the regulation of the ovarian 17-hydroxylase and C-17,20,20-lyase activities is abnormal in such women. Expand
Growth hormone therapy of Turner's syndrome: beneficial effect on adult height.
GH, either alone or in combination with OX, is capable of stimulating short-term growth and augmenting adult height in girls with TS and with early diagnosis and initiation of treatment, an adult height of more than 150 cm is a reasonable goal for most girls withTS. Expand
Six-year results of a randomized, prospective trial of human growth hormone and oxandrolone in Turner syndrome.
It is concluded that therapy with hGH, alone and in combination with oxandrolone, can result in a sustained increase in growth rate and a significant increase in adult height for most prepubertal girls with Turner syndrome. Expand
A new test of combined pituitary-testicular function using the gonadotropin-releasing hormone agonist nafarelin in the differentiation of gonadotropin deficiency from delayed puberty: pilot studies.
It is suggested that the response to a single test dose of nafarelin distinguishes GD from DP in the teenage years as well as does measurement of nocturnal LH levels and the testosterone response to the GnRH agonist adds a new dimension to GnRH testing. Expand
Preserving adult height potential in girls with idiopathic true precocious puberty.
It is indicated that gonadotropin releasing hormone agonist therapy preserves height potential in girls with an initially impaired height prognosis, and that height potential is preserved without therapy in those with a good initial height prog outlook. Expand
Outcomes of growth hormone replacement therapy in survivors of childhood acute lymphoblastic leukemia.
  • W. Leung, S. Rose, +8 authors C. Pui
  • Medicine
  • Journal of clinical oncology : official journal…
  • 1 July 2002
It is suggested that GH replacement therapy is safe and efficacious for the correction of GH deficiency in survivors of childhood ALL. Expand
Three-year results of a randomized prospective trial of methionyl human growth hormone and oxandrolone in Turner syndrome.
Girls with Turner syndrome participated in a prospective, randomized study to determine the effects on growth of methionyl human growth hormone (met-hGH) or oxandrolone, and predicted adult height by the method of Bayley-Pinneau increased after 3 years of treatment. Expand
Hypergonadotropism in peripubertal boys with chronic renal failure.
Elevated serum LH concentrations in the presence of normal serum testosterone concentrations imply limited testicular sensitivity to the effects of LH in these peripubertal boys, as has been documented for adult men with chronic renal failure. Expand
Growth hormone deficiency impedes the rise in plasma insulin-like growth factor I levels associated with precocious puberty.
The onset of precocious puberty in children with organic GH deficiency may mask the abnormal growth pattern of these children and delay diagnosis; determinations of plasma IGF-I concentrations may be helpful in assessing the GH status of these patients. Expand