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CYP8B1 protein, human

Known as: Steroid 12-Alpha-Hydroxylase, Cytochrome P450 Family 8 Subfamily B Polypeptide 1, 7-Alpha-Hydroxycholest-4-En-3-One 12-Alpha-Hydroxylase 
7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (501 aa, ~58 kDa) is encoded by the human CYP8B1 gene. This protein is involved in bile acid… 
National Institutes of Health

Related topics

Related topics

12 relations
Bile Acid Biosynthesis PathwayCYP8B1 geneEnzyme GeneHemeproteins

Broader (1)

Sterol 12-alpha-Hydroxylase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Influence of dietary sugar on cholesterol and bile acid metabolism in the rat: Marked reduction of hepatic Abcg5/8 expression following sucrose ingestion.
2014
2014
Penerapan Pembelajaran Matematika Realistik dengan Whole Brain Teaching pada Pokok Bahasan Teorema Pythagoras untuk Meningkatkan Hasil Belajar dan Aktivitas Siswa Tunarungu Kelas VIIIB SMPLB Sinar…
Abstrak. Penelitian ini bertujuan untuk mengetahui: (1) penerapan pembelajaran yang digunakan pada pokok bahasan Teorema… 
2014
2014
Transcriptional regulation of aldo-keto reductase 1D1
Bile acids are physiological detergents and surfactants with recently identified roles as signaling hormones. Maintenance of… 
2010
2010
PENERAPAN PENDEKATAN BELAJAR KELOMPOKDALAM PEMBELAJARAN AQIDAH AKHLAKDI MTs ANA MUSLIM KUNTO DARUSSALAMKABUPATEN ROKAN HULU
Penelitian ini bertujuan mengetahui efektivitas penerapan metode belajar kelompok pada pembelajaran Aqidah Akhlak di Madrasah… 
2006
2006
βKlotho: A new kid on the bile acid biosynthesis block
We have generated a line of mutant mouse that lacks βKlotho, a protein that structurally resembles Klotho. The synthesis and… 
2006
2006
Two loci on chromosome 9 control bile acid composition: evidence that a strong candidate gene, Cyp8b1, is not the culprits⃞ Published, JLR Papers in Press, June 8, 2006.
An intercross between C57BL/6J and CASA/Rk mice was used to study the genetics of biliary bile acid composition. In parental… 
2003
2003
Gene structure of pig sterol 12alpha-hydroxylase (CYP8B1) and expression in fetal liver: comparison with expression of taurochenodeoxycholic acid 6alpha-hydroxylase (CYP4A21).
2000
2000
Regulation of sterol 12alpha-hydroxylase and cholic acid biosynthesis in the rat.
BACKGROUND & AIMS Sterol 12alpha-hydroxylase (CYP8b1) is required for the biosynthesis of cholic acid (CA) and hence helps… 
Highly Cited
1999
Highly Cited
1999
Structure and chromosomal assignment of the sterol 12alpha-hydroxylase gene (CYP8B1) in human and mouse: eukaryotic cytochrome P-450 gene devoid of introns.
Sterol 12alpha-hydroxylase (CYP8B1) is a hepatic cytochrome P-450 that controls the ratio of cholic acid over chenodeoxycholic… 
1975
1975
Conversion of 7alpha-hydroxycholesterol and 7alpha-hydroxy-beta-sitosterol to 3alpha, 7alpha-dihydroxy- and 3alpha, 7alpha, 12alpha-trihydroxy-5beta-steroids in vitro.
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