Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Sterol 12-alpha-Hydroxylase

Known as: Steroid 12-alpha-Hydroxylase, Steroid, hydrogen-donor:oxygen oxidoreductase (12-alpha-hydroxylating), 12alpha-Hydroxylase 
A liver microsomal cytochrome P450 enzyme that catalyzes the 12-alpha-hydroxylation of a broad spectrum of sterols in the presence of molecular… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Liver receptor homolog 1 (LRH-1), an orphan nuclear receptor, is highly expressed in liver and intestine, where it is implicated… Expand
  • figure 1
  • table 1
  • table 2
  • table 3
  • table 4
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Bile acid concentrations are controlled by a feedback regulatory pathway whereby activation of the farnesoid X receptor (FXR… Expand
  • figure 2
  • figure 1
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Cafestol, a diterpene present in unfiltered coffee brews such as Scandinavian boiled, Turkish, and cafetière coffee, is the most… Expand
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 4
Is this relevant?
Highly Cited
2005
Highly Cited
2005
We have generated a line of mutant mouse that lacks betaKlotho, a protein that structurally resembles Klotho. The synthesis and… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Guggulipid is an extract of the guggul treeCommiphora mukul and has been widely used to treat hyperlipidemia in humans. The plant… Expand
  • figure 1
  • figure 2
  • figure 5
  • figure 4
  • table I
Is this relevant?
Highly Cited
2003
Highly Cited
2003
The bile salt-activated farnesoid X receptor (FXR; NR1H4) controls expression of several genes considered crucial in maintenance… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Cholesterol is converted into dozens of primary and secondary bile acids through pathways subject to negative feedback regulation… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
The nuclear oxysterol-receptor paralogues LXRalpha and LXRbeta share a high degree of amino acid identity and bind endogenous… Expand
  • figure 1
  • figure 2
  • table 1
  • figure 3
  • figure 4
Is this relevant?
Review
1998
Review
1998
  • J. Chiang
  • Frontiers in bioscience : a journal and virtual…
  • 1998
  • Corpus ID: 40120546
Bile acids are important physiological agents required for disposal of cholesterol and absorption of vitamins and fats. Bile… Expand
Is this relevant?
Highly Cited
1976
Highly Cited
1976
The effects of chenodeoxycholic (CDC), 750 mg. per day, phenobarbital (PB), 90 or 180 mg., combined (CDC + PB), and placebo on… Expand
Is this relevant?