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CYP8B1 gene

Known as: cytochrome P450 family 8 subfamily B member 1, CYP8B1, STEROL 12-ALPHA-HYDROXYLASE 
This gene plays a role in steroid metabolism and regulation of cholesterol solubility.
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Anabolic–androgenic steroids are testosterone derivatives, used by body-builders to increase muscle mass. Epistane (EPI) is an… 
2019
2019
Background Type 2 diabetes has become one of the most common diseases worldwide, causing a serious social burden. As a first-line… 
2019
2019
The CYP8B1 gene is known to catalyse reactions that determine the ratio of primary bile salts and the loss of this gene has… 
2019
2019
Hepatocellular carcinoma (HCC) is a lethal malignancy with high morbidity and mortality rates worldwide. The identification of… 
2018
2018
BackgroundRitodrine is a commonly used tocolytic to prevent preterm labour. However, it can cause unexpected serious adverse… 
2013
2013
Gallstone disease (GD) is a common disease of multigenetic origin; however, the major susceptibility loci for GD in human… 
2007
2007
Dissolution of N-iodosuccinimide in sulfuric acid gives rise to electrophilic iodine-containing species which are capable of… 
Highly Cited
2006
Highly Cited
2006
Hepatocyte nuclear factor 4alpha (HNF4alpha) regulates many genes that are preferentially expressed in liver. Mice lacking… 
Highly Cited
2006
Highly Cited
2006
As previously reported by us, mice with targeted disruption of the CYP8B1 gene (CYP8B1−/−) fail to produce cholic acid (CA… 
2006
2006
An intercross between C57BL/6J and CASA/Rk mice was used to study the genetics of biliary bile acid composition. In parental…