CYP8B1 gene

Known as: cytochrome P450 family 8 subfamily B member 1, CYP8B1, STEROL 12-ALPHA-HYDROXYLASE 
This gene plays a role in steroid metabolism and regulation of cholesterol solubility.
National Institutes of Health

Papers overview

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2019
2019
Hepatocellular carcinoma (HCC) is a lethal malignancy with high morbidity and mortality rates worldwide. The identification of… (More)
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2018
2018
Ritodrine is a commonly used tocolytic to prevent preterm labour. However, it can cause unexpected serious adverse reactions… (More)
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2015
2015
Bile acids, the major products of hepatic cholesterol catabolism, are indispensable for lipid absorption and cholesterol… (More)
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2013
2013
BACKGROUND AND AIMS Gallstone disease (GD) is a common disease of multigenetic origin; however, the major susceptibility loci for… (More)
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2011
2011
The spontaneously hypertensive rat (SHR)/NDmcr-cp (SHR-cp), which is a metabolic syndrome model rat, was reported to show… (More)
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2006
2006
As previously reported by us, mice with targeted disruption of the CYP8B1 gene (CYP8B1-/-) fail to produce cholic acid (CA… (More)
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Highly Cited
2006
Highly Cited
2006
Hepatocyte nuclear factor 4alpha (HNF4alpha) regulates many genes that are preferentially expressed in liver. Mice lacking… (More)
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2006
2006
An intercross between C57BL/6J and CASA/Rk mice was used to study the genetics of biliary bile acid composition. In parental… (More)
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2005
2005
OBJECTIVE In humans, two primary bile acids are synthesized: cholic acid (CA) and chenodeoxycholic acid (CDCA), the first and… (More)
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