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CYP46A1 cholesterol 24-hydroxylase activity

Known as: CYP46A1 
National Institutes of Health

Papers overview

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2016
2016
Brain is the cholesterol-richest organ and contains one fourth of the total body cholesterol. The majority of brain cholesterol… 
2015
2015
A series of imidazo[1,2-a]pyridine analogs that effectively inhibit cholesterol 24-hydroxylase (CYP46A1) was reported in… 
2015
2015
The retina is responsible for coding the light stimulus into a nervous signal that is transferred to the brain via the optic… 
2013
2013
Cytochrome P450 46A1 (CYP46A1) is a brainspecific cholesterol 24-hydroxylase responsible for the majority of cholesterol… 
2009
2009
Cytochrome P450 46A1 (CYP46A1) is a key enzyme responsible for cholesterol elimination from the brain. This P450 can interact… 
Review
2009
Review
2009
Cytochrome P450 enzymes (CYPs) belong to hemeproteins found in all living organisms. In eucaryotic cells they are responsible for… 
2007
2007
Aging is one of the most significant risk factors for neurological disorders including Alzheimer's Disease (late-onset AD and…