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cholesterol 24-hydroxylase activity

Known as: cholesterol 24-monooxygenase activity, cholesterol 24S-hydroxylase activity, CYP46 
Catalysis of the reaction: cholesterol + H(+) + NADPH + O(2) = (24S)-24-hydroxycholesterol + H(2)O + NADP(+). [EC:1.14.13.98, RHEA:22719]
National Institutes of Health

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3 relations
CYP46A1 cholesterol 24-hydroxylase activityCytochrome P450 Family 46cholesterol 24-hydroxylase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
P4-8 The effects of cholesterol and CYP46 polymorphism on cognitive event-related potentials
Review
2009
Review
2009
Cyp46 Polymorphisms in Alzheimer’s Disease: A Review
Increasing research findings argue for a link between brain cholesterol turnover and Alzheimer’s disease (AD). High cerebral… 
Review
2007
Review
2007
Plasma 24S Hydroxycholesterol Response to Statins in Alzheimer’s Disease Patients: Effects of Gender, CYP46, and ApoE Polymorphisms
A number of epidemiologic studies suggest an association between plasma total cholesterol and risk for Alzheimer’s disease (AD… 
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