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CI 1000

Known as: CI-1000 
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
The findings of the accompanying paper (Németi and Gregus, Toxicol: Sci. 70, 4-12) indicate that the arsenate (AsV) reductase… 
1995
1995
Rats received daily oral doses of 15, 50, 150, or 200 mg/kg CI-1000 for 4 weeks. Doses were selected based on findings from a 2… 
1994
1994
Purine nucleoside Phosphorylase (PNP) is a purine salvage enzyme that catalyzes the reversible phosphorylation of guanine and… 
1994
1994
Purine nucleosides HxR or GdR (2.5 micrograms/mL blood) were added to EDTA-treated cynomolgus monkey whole blood in vitro, alone… 
1994
1994
CI-1000, a 9-deazaguanine analog, is an orally active and reversible inhibitor of purine nucleoside Phosphorylase (PNP). In vitro… 
1994
1994
Patients with homozygous deficiency of purine nucleoside phosphorylase (PNP) present with a T‐cell selective immune deficiency…