CHEK2 wt Allele

Known as: CDS1, PP1425, CHK2 
Human CHEK2 wild-type allele is located in the vicinity of 22q12.1 and is approximately 57 kb in length. This allele, which encodes serine/threonine… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2016
02419962016

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2014
2014
The 33 genes in the Saccharomyces cerevisiae mitotic CLB2 transcription cluster have been known to be downregulated by the DNA… (More)
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2010
2010
To maintain genomic integrity cells have to respond properly to a variety of exogenous and endogenous factors that produce genome… (More)
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2010
2010
Studies in budding yeast suggest the protein kinase Rad53 plays novel roles in controlling initiation of DNA replication and in… (More)
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2006
2006
A novel role for Rad53 in the initiation of DNA replication that is independent of checkpoint or deoxynucleotide regulation is… (More)
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2005
2005
Saccharomyces cerevisiae RAD53 (CHK2) and CHK1 control two parallel branches of the RAD9-mediated pathway for DNA damage-induced… (More)
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Highly Cited
1999
Highly Cited
1999
Eukaryotic cells coordinate chromosome duplication by assembly of protein complexes at origins of DNA replication and by… (More)
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1999
1999
Eukaryotic checkpoint genes regulate multiple cellular responses to DNA damage. In this report, we examine the roles of budding… (More)
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1999
1999
The Cdc7p and Dbf4p proteins form an active kinase complex in Saccharomyces cerevisiae that is essential for the initiation of… (More)
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1998
1998
In budding yeast, RAD9 and RAD24/RAD17/MEC3 are believed to function upstream of MEC1 and RAD53 in signalling the presence of DNA… (More)
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Highly Cited
1996
Highly Cited
1996
Mutants of the Saccharomyces cerevisiae ataxia telangiectasia mutated (ATM) homolog MEC1/SAD3/ESR1 were identified that could… (More)
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