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CHEK2 wt Allele

Known as: CDS1, PP1425, CHK2 
Human CHEK2 wild-type allele is located in the vicinity of 22q12.1 and is approximately 57 kb in length. This allele, which encodes serine/threonine… 
National Institutes of Health

Related topics

Related topics

19 relations
22q12.1ATM Signaling PathwayBrain NeoplasmsCHEK2 protein, human

Broader (1)

CHEK2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Previously uncharacterized amino acid residues in histone H3 and H4 mutants with roles in DNA damage repair response and cellular aging
Chromatin regulates gene expression and genome maintenance, and consists of histones and other components. The post‐translational… 
2016
2016
Sds22 participates in Glc7 mediated Rad53 dephosphorylation in MMS-induced DNA damage in Candida albicans.
2011
2011
In vivo radiobiological characterization of proton beam at the National Cancer Center in Korea: effect of the Chk2 mutation.
2011
2011
Redundant Mechanisms Prevent Mitotic Entry Following Replication Arrest in the Absence of Cdc25 Hyper-Phosphorylation in Fission Yeast
Following replication arrest the Cdc25 phosphatase is phosphorylated and inhibited by Cds1. It has previously been reported that… 
2010
2010
A Strategy for Interaction Site Prediction between Phospho-binding Modules and their Partners Identified from Proteomic Data*
Small and large scale proteomic technologies are providing a wealth of potential interactions between proteins bearing phospho… 
2007
2007
Mus81 functions in the quality control of replication forks at the rDNA and is involved in the maintenance of rDNA repeat number in Saccharomyces cerevisiae.
Review
2005
Review
2005
Taming the Spindle for Containing the Chromosomes
Checkpoint controls are critical for coordination of cell cycle events, especially during exposure to perturbations or stresses… 
2002
2002
Precocious S-phase entry in budding yeast prolongs replicative state and increases dependence upon Rad53 for viability.
Precocious entry into S phase due to overproduction of G1 regulators can cause genomic instability. The mechanisms of this… 
2001
2001
Cell Cycle Arrest Determines the Intensity of the Global Transcriptional Response of Saccharomyces cerevisiae to Ionizing Radiation
Abstract De Sanctis, V., Bertozzi, C., Costanzo, G., Di Mauro, E. and Negri, R. Cell Cycle Arrest Determines the Intensity of the… 
Highly Cited
1999
Highly Cited
1999
RAD53 regulates DBF4 independently of checkpoint function in Saccharomyces cerevisiae.
The Cdc7p and Dbf4p proteins form an active kinase complex in Saccharomyces cerevisiae that is essential for the initiation of… 
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