CGP 41251

Known as: CGP 41 251, CGP-41251 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2017
024619922017

Papers overview

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1998
1998
CGP, 41251, a staurosporine derivative, is a potent inhibitor of protein kinase C (PKC). In recent studies we found that this… (More)
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1998
1998
It has been shown previously that the staurosporine derivative CGP 41251, a specific inhibitor of protein kinase C (IC50 = 50 nM… (More)
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1997
1997
The substance P (SP) receptor (NK-1 subtype) is widely expressed in primary human astrocytomas and glioblastomas and many brain… (More)
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1996
1996
Protein kinase C (PKC) plays a central role in signal transduction pathways that mediate the action of certain growth factors… (More)
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1996
1996
Added to HeLa cells previously exposed to recombinant human interferon (IFN)-gamma for 20 h, thyroid hormone [L-thyroxine (T4… (More)
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1996
1996
The potent kinase inhibitor staurosporine and its protein kinase C (PKC)-selective analogue CGP 41251 are known to sensitise… (More)
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1995
1995
We evaluated the therapeutic efficacy against murine drug-sensitive and drug-resistant tumor of a combination chemotherapy… (More)
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1995
1995
Melanoma cells express receptors for melanocyte-stimulating hormone (MSH) in variable abundance. CGP 41251, a derivative of… (More)
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1994
1994
Multidrug resistance (MDR) is frequently associated with overexpression of a 170-kDa P-glycoprotein (Pgp). Data suggest altered… (More)
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1992
1992
The microbial alkaloid staurosporine is a potent but nonselective inhibitor of protein kinases. The derivative CGP 41251 has been… (More)
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