CFLAR gene

Known as: I-FLICE, CASP8 and FADD like apoptosis regulator, CASP8- AND FADD-LIKE APOPTOSIS REGULATOR 
This gene plays a role in the regulation of both proteolysis and apoptosis.

Topic mentions per year

Topic mentions per year

1950-2017
020406019502016

Papers overview

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Highly Cited
2016
Highly Cited
2016
BACKGROUND Most guidelines recommend either a long-acting beta-agonist (LABA) plus an inhaled glucocorticoid or a long-acting… (More)
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Hemiplegia and hemiparesis are the most common deficits caused by stroke. A few small clinical trials suggest that… (More)
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Highly Cited
2010
Highly Cited
2010
Driven by the availability of experimental data and ability to simulate a biological scale which is of immediate interest, the… (More)
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Highly Cited
2006
Highly Cited
2006
Data clustering analysis has been extensively applied to extract information from gene expression profiles obtained with DNA… (More)
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Highly Cited
2002
Highly Cited
2002
Death receptors, such as Fas and tumor necrosis factor-related apoptosis-inducing ligand receptors, recruit Fas-associated death… (More)
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Highly Cited
2002
Highly Cited
2002
Does distraction or rumination work better to diffuse anger? Catharsis theory predicts that rumination works best, but empirical… (More)
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Highly Cited
2002
Highly Cited
2002
Type 2 diabetes mellitus results from an inadequate adaptation of the functional pancreatic beta cell mass in the face of insulin… (More)
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Highly Cited
2001
Highly Cited
2001
The caspase-8 homologue FLICE-inhibitory protein (FLIP) functions as a caspase-8 dominant negative, blocking apoptosis induced by… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Activation of Fas (CD95) by its ligand (FasL) rapidly induces cell death through recruitment and activation of caspase… (More)
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Highly Cited
1999
Highly Cited
1999
The induction of apoptosis by death receptors serves to regulate immune responses by eliminating unwanted and harmful cells… (More)
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