CASP8 and FADD-Like Apoptosis Regulator Protein

Known as: I-FLICE, Casper, Cellular FLICE-Like Inhibitory Protein Long Isoform 
CASP8 and FADD-like apoptosis regulator (480 aa, ~55 kDa) is encoded by the human CFLAR gene. This protein plays a role in the inhibition of caspase… (More)
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
Caspase-8, the initiator caspase of the death receptor pathway of apoptosis, its adapter molecule, FADD, required for caspase-8… (More)
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Highly Cited
2007
Highly Cited
2007
This paper investigates whether stock prices reflect information about future earnings contained in the accrual and cash flow… (More)
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Highly Cited
2005
Highly Cited
2005
c-FLIPs (c-FLICE inhibitory proteins) play an essential role in regulation of death receptor-induced apoptosis. Multiple splice… (More)
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Highly Cited
2002
Highly Cited
2002
Activation of the caspase cascade is a pivotal step in apoptosis and can occur via death adaptor-mediated homo-oligomerization of… (More)
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Highly Cited
2000
Highly Cited
2000
Conventional wisdom asserts that firms with large cash holdings are likely takeover targets. Using hostile takeover activity from… (More)
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Highly Cited
1999
Highly Cited
1999
Upon stimulation, CD95 (APO-1/Fas) recruits the adapter molecule Fas-associated death domain protein (FADD)/MORT1 and caspase-8… (More)
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Highly Cited
1997
Highly Cited
1997
No. This paper investigates the relationship between financing constraints and investment-cash flow sensitivities by analyzing… (More)
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Highly Cited
1997
Highly Cited
1997
Caspases are cysteine proteases that play a central role in apoptosis. Caspase-8 may be the first enzyme of the proteolytic… (More)
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Highly Cited
1997
Highly Cited
1997
We identified and cloned a novel human protein that contains FADD/Mort1 death effector domain homology regions, designated FLAME… (More)
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Highly Cited
1997
Highly Cited
1997
We have identified and characterized CLARP, a caspase-like apoptosis-regulatory protein. Sequence analysis revealed that human… (More)
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