CFLAR wt Allele

Known as: I-FLICE, CASP8AP1, Casper 
Human CFLAR wild-type allele is located within 2q33-q34 and is approximately 48 kb in length. This allele, which encodes CASP8 and FADD-like… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Intrinsic Physical Unclonable Functions or PUFs have been introduced as a highly secure method to extract digital identifiers and… (More)
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Highly Cited
2006
Highly Cited
2006
The proinflammatory cytokine tumor necrosis factor (TNF) alpha signals both cell survival and death. The biological outcome of… (More)
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Highly Cited
2005
Highly Cited
2005
c-FLIPs (c-FLICE inhibitory proteins) play an essential role in regulation of death receptor-induced apoptosis. Multiple splice… (More)
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Highly Cited
2004
Highly Cited
2004
Caspase 8 is required not only for death receptor-mediated apoptosis but also for lymphocyte activation in the immune system… (More)
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Highly Cited
2002
Highly Cited
2002
TRAIL (Apo2 ligand) is a member of the tumor necrosis factor (TNF) family of cytokines that induces apoptosis. Because TRAIL… (More)
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Highly Cited
2001
Highly Cited
2001
Activation of the transcription factor NF-kappaB is a major effector of the inducible resistance to death receptor-mediated… (More)
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Highly Cited
2000
Highly Cited
2000
The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL or Apo2L) is a potent inducer of death of cancer but not… (More)
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Highly Cited
2000
Highly Cited
2000
Caspase-8 plays an essential role in apoptosis triggered by death receptors. Through the cleavage of Bid, a proapoptotic Bcl-2… (More)
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Highly Cited
1999
Highly Cited
1999
Death receptor-mediated apoptosis can be modulated by several antiapoptotic proteins, such as the FLICE (FADD [Fas-associated… (More)
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Highly Cited
1997
Highly Cited
1997
We have identified and characterized CLARP, a caspase-like apoptosis-regulatory protein. Sequence analysis revealed that human… (More)
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