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CFLAR protein, human

Known as: CLARP protein, human, Cellular FLICE-Like Inhibitory Protein Short Isoform, MACH-Related Inducer of Toxicity Beta-1 
CASP8 and FADD-like apoptosis regulator isoform 2 (221 aa, ~25 kDa) is encoded by the human CFLAR gene. This protein is involved in the regulation of… 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Triple-negative breast cancers (TNBCs) are clinically aggressive forms associated with a poor prognosis. We evaluated the… 
Review
2011
Review
2011
Cellular FLICE (FADD-like IL-1beta-converting enzyme)-inhibitory protein (c-FLIP) is a major resistance factor and critical anti… 
Highly Cited
2008
Highly Cited
2008
This study demonstrates that combined treatment with subtoxic doses of quercetin (3′,3′,4′,5,7‐pentahydroxyflavone), a flavonoid… 
Highly Cited
2006
Highly Cited
2006
c-FLIP inhibits caspase 8 activation and apoptosis mediated by death receptors such as Fas and DR5. We studied the effect of c… 
Highly Cited
2003
Highly Cited
2003
Tumors display a high rate of glucose uptake and glycolysis. We investigated how inhibition of glucose metabolism could affect… 
Highly Cited
2002
Highly Cited
2002
Primary B cells from B cell chronic lymphocytic leukaemia (B-CLL) were resistant to the novel selective cytotoxic agent, TNF… 
Highly Cited
2000
Highly Cited
2000
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a potent inducer of apoptosis of transformed and cancer cells…