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CFLAR protein, human

Known as: CLARP protein, human, Cellular FLICE-Like Inhibitory Protein Short Isoform, MACH-Related Inducer of Toxicity Beta-1 
CASP8 and FADD-like apoptosis regulator isoform 2 (221 aa, ~25 kDa) is encoded by the human CFLAR gene. This protein is involved in the regulation of… 
National Institutes of Health

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Related topics

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ApoptosisCASP8 and FADD-Like Apoptosis Regulator ProteinCFLAR geneCaspase-Dependent Apoptosis

Broader (1)

CASP8 and FADD-Like Apoptosis Regulating Protein

Papers overview

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2020
2020
Backbone and side-chain chemical shift assignments of a cellular FLICE-inhibitory protein (c-FLIPS)
Cellular FLICE-inhibitory protein (c-FLIP), which is involved in regulating the apoptosis of the extrinsic cell death pathway… 
2014
2014
Expression of cFLIPS: disulfure bridges and activity
c-FLIPS and FADD are two human proteins involved in apoptosis. Binding of c-FLIPS to FADD over DED domains prevents binding of… 
Review
2012
Review
2012
MASTER ANTI-APOPTOTIC REGULATOR
Cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein (c-FLIP) is a master anti-apoptotic regulator and… 
2009
2009
GLUT 1-induced cFLIP expression promotes proliferation and prevents apoptosis in vascular smooth muscle cells
Vesely ED, Heilig CW, Brosius FC III. GLUT1-induced cFLIP expression promotes proliferation and prevents apoptosis in vascular… 
2007
2007
TRAIL Resistance in Human Glioma Death-Inducing Signaling Complex and Contributes to to theS Recruits FLIP α Heat Shock Protein 90
Heat shock protein 90 (HSP90) is a molecular chaperone that contributes to the proper folding and stability of target proteins… 
2007
2007
c-FLIP and Survivin Apoptosis via DR5 Up-regulation and Down-regulation of Silibinin Sensitizes Human Glioma Cells to TRAIL-Mediated
Silibinin, a flavonoid isolated from Silybum marianum , has been reported to have cancer chemopreventive and therapeutic effects… 
2007
2007
NSCLC Cells Up-Regulation of c-FLIP and Survivin Expression in Human Enhancement of TRAIL-Induced Apoptosis Despite DR 5 Expression Leading to Induction of Apoptosis and The Proteasome Inhibitor PS…
The proteasome inhibitor PS-341 (bortezomib or Velcade), an approved drug for treatment of patients with multiple myeloma, is… 
2004
2004
LIGHT FLIPS THE LIPID SWITCH
2002
2002
DIAGONAL FLIPS IN GRAPHS ON CLOSED SURFACES WITH SPECIFIED FACE SIZE DISTRIBUTIONS
. We shall show that two simple graphs embedded on a closed surface with the same face size distribution can be transformed into… 
1998
1998
ECOSYSTEM FLIPS IN CULTURAL LANDSCAPES : THE CASE OF KOLLI HILLS
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