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CDK9 protein, human

Known as: CDK-9 protein, human, Tat-Associated Kinase Complex Catalytic Subunit, C-2K 
Cyclin-dependent kinase 9 (372 aa, ~43 kDa) is encoded by the human CDK9 gene. This protein plays a role in the positive regulation of… 
National Institutes of Health

Related topics

Related topics

23 relations
CDK12 protein, humanCDK2 protein, humanCDK3 protein, humanCDK4 protein, human

Broader (1)

Cyclin-Dependent Kinase 9

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Chemically induced degradation of CDK9 by a proteolysis targeting chimera (PROTAC).
Cyclin-dependent kinase 9 (CDK9), a member of the cyclin-dependent protein kinase (CDK) family, is involved in transcriptional… 
Highly Cited
2011
Highly Cited
2011
Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1
The wogonin-containing herb Scutellaria baicalensis has successfully been used for curing various diseases in traditional Chinese… 
Highly Cited
2011
Highly Cited
2011
CD4+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21.
Elite controllers represent a unique group of HIV-1-infected persons with undetectable HIV-1 replication in the absence of… 
Highly Cited
2010
Highly Cited
2010
Crosstalk between mRNA 3' end processing and transcription initiation.
Review
2008
Review
2008
Cyclin-dependent kinase 9: a key transcriptional regulator and potential drug target in oncology, virology and cardiology.
Highly Cited
2001
Highly Cited
2001
Three RNA Polymerase II Carboxyl-terminal Domain Kinases Display Distinct Substrate Preferences*
CDK7, CDK8, and CDK9 are cyclin-dependent kinases (CDKs) that phosphorylate the C-terminal domain (CTD) of RNA polymerase II… 
Highly Cited
2000
Highly Cited
2000
Tat Modifies the Activity of CDK9 To Phosphorylate Serine 5 of the RNA Polymerase II Carboxyl-Terminal Domain during Human Immunodeficiency Virus Type 1 Transcription
ABSTRACT Tat stimulates human immunodeficiency virus type 1 (HIV-1) transcriptional elongation by recruitment of carboxyl… 
Highly Cited
1999
Highly Cited
1999
Cyclin K Functions as a CDK9 Regulatory Subunit and Participates in RNA Polymerase II Transcription*
Important progress in the understanding of elongation control by RNA polymerase II (RNAPII) has come from the recent… 
Highly Cited
1998
Highly Cited
1998
Identification of multiple cyclin subunits of human P-TEFb.
The transition from abortive into productive elongation is proposed to be controlled by a positive transcription elongation… 
Highly Cited
1998
Highly Cited
1998
Transcription elongation factor P‐TEFb mediates Tat activation of HIV‐1 transcription at multiple stages
Tat stimulates human immunodeficiency virus type 1 (HIV‐1) transcription elongation through recognition of the transactivation… 
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