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CDK6 gene

Known as: Cyclin-Dependent Kinase 6 Gene, CYCLIN-DEPENDENT KINASE 6, PLSTIRE 
This gene plays a role in the progression of the cell cycle.
National Institutes of Health

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Related topics

9 relations
CDK6 protein, humanCell Cycle ControlNegative Regulation of Cell CyclePhosphorylation

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CDK6 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Long noncoding RNA nuclear enriched abundant transcript 1 impacts cell proliferation, invasion, and migration of glioma through regulating miR‐139‐5p/ CDK6
Aims: We aimed to explore the impact of long noncoding RNA (lncRNA) nuclear enriched abundant transcript 1 (NEAT1) on cell… 
2015
2015
MicroRNA-29b is a Novel Prognostic Marker in Colorectal Cancer
PurposeRecent studies have suggested that microRNA-29 (miR-29) family members may play important roles in human cancer by… 
Highly Cited
2015
Highly Cited
2015
H19 derived microRNA-675 regulates cell proliferation and migration through CDK6 in glioma.
The long non-coding RNA (LncRNA) H19 is one of the most highly abundant and conserved transcripts involved in the mammalian… 
2015
2015
Novel Candidate Key Drivers in the Integrative Network of Genes, MicroRNAs, Methylations, and Copy Number Variations in Squamous Cell Lung Carcinoma
The mechanisms of lung cancer are highly complex. Not only mRNA gene expression but also microRNAs, DNA methylation, and copy… 
Highly Cited
2011
Highly Cited
2011
Deregulation of FGFR1 and CDK6 oncogenic pathways in acute lymphoblastic leukaemia harbouring epigenetic modifications of the MIR9 family
The role of epigenetic mechanisms in the regulation of microRNAs (miRNAs) with a tumour‐suppressor function in human neoplasms… 
Highly Cited
2011
Highly Cited
2011
miR-191 down-regulation plays a role in thyroid follicular tumors through CDK6 targeting.
CONTEXT Well-differentiated thyroid carcinomas include papillary (PTC) and follicular (FTC) carcinomas. FTC is usually a more… 
Highly Cited
2007
Highly Cited
2007
CDK4 and CDK6 Delay Senescence by Kinase-Dependent and p16INK4a-Independent Mechanisms
ABSTRACT Replicative senescence of human diploid fibroblasts (HDFs) is largely implemented by the cyclin-dependent kinase (CDK… 
Highly Cited
2003
Highly Cited
2003
A new indole-3-carbinol tetrameric derivative inhibits cyclin-dependent kinase 6 expression, and induces G1 cell cycle arrest in both estrogen-dependent and estrogen-independent breast cancer cell…
Indole-3-carbinol (I3C), autolysis product of glucosinolates present in cruciferous vegetables, has been indicated as a promising… 
Highly Cited
2003
Highly Cited
2003
Expression of cyclin-dependent kinase 6, but not cyclin-dependent kinase 4, alters morphology of cultured mouse astrocytes.
Disruption of the pRb pathway is a common mechanism in tumor formation. The D-cyclin-associated kinases, cyclin-dependent kinase… 
Highly Cited
2000
Highly Cited
2000
Expression of p19INK4d, CDK4, CDK6 in glioblastoma multiforme.
Deregulation of the G1/S checkpoint is a frequent event in the development of glioblastoma multiforme (GBM). Previous studies… 
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