Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 234,930,620 papers from all fields of science
Search
Sign In
Create Free Account
CDK6 protein, human
Known as:
cyclin-dependent kinase 6, human
, PLSTIRE protein, human
, Serine/Threonine-Protein Kinase PLSTIRE
Expand
Cyclin-dependent kinase 6 (326 aa, ~37 kDa) is encoded by the human CDK6 gene. This protein plays a role in both protein phosphorylation and cell…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
18 relations
CDK6 gene
Cell Cycle
Cell Cycle Control
Cell Nucleus
Expand
Broader (1)
cyclin-dependent kinase 6
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Molecular Medicine Role of CDK 6 and FOXO 3 in ovarian cancer
A. Dall
,
Acqua
2017
Corpus ID: 32843057
Figure EV1. CDK6 knockdown sensitizes OVCAR8 cells to platinum-induced cell death. A Table summarizing CDDP and CBDCA IC50 of…
Expand
2017
2017
Abstract 5862: YAP1 mediated CDK6 activation confers radiation resistance in esophageal cancer: rationale for the combination of YAP1 and CDK4/6 inhibitors in EC
Fan Li
,
Xiaoquan Dong
,
+8 authors
J. Ajani
2017
Corpus ID: 79891211
2015
2015
High expression of CDK6 protects breast cancer cells from fulvestrant-mediated apoptosis and is a predictor of resistance to fulvestrant treatment in estrogen receptor-positive metastatic breast…
Carla L. Alves
,
Daniel Elías
,
M. Lyng
,
M. Bak
,
A. Lykkesfeldt
,
H. Ditzel
2015
Corpus ID: 57386585
2015
2015
Metabolic reprogramming and vulnerabilities of prostate cancer stem cells independent or epithelial-mesenchymal transition
Esther Aguilar Fadó
2015
Corpus ID: 82241126
Metastasis represents the most life-threatening aspect of tumorigenesis and is the leading cause of death by cancer. Intensive…
Expand
2011
2011
Combination of flavopiridol and embelin effectively inhibit cell growth in hepatocellular carcinoma depending on regulatory relationship between CDK6 and XIAP
Yufang Che
,
David Y. Zhang
,
F. Ye
,
Benyan Wu
,
B. Jiang
Medicinal Chemistry Research
2011
Corpus ID: 253632481
Flavopiridol, as a cyclin-dependent kinase (CDK) inhibitor, has entered into phase II study of clinical trial in chronic…
Expand
2009
2009
Inhibitor That Shows Antitumor Activity The Development of a Selective Cyclin-Dependent Kinase
Simak Ali
,
D. Heathcote
,
+14 authors
R. Coombes
2009
Corpus ID: 53374793
Normal progression through the cell cycle requires the sequential action of cyclin-dependent kinases CDK1, CDK2, CDK4, and CDK6…
Expand
2007
2007
Expression of CCND1, P16 and CDK6 in Human Basal Cell Carcinoma
S. Eshkoor
2007
Corpus ID: 81064692
Basal cell carcinoma (BCC) is the most common cancer among skin cancers. The incidence of cutaneous malignant melanoma (CMM) and…
Expand
2005
2005
Adenovirus-mediated Gene Therapy for Human Head and Neck Squamous Cell Cancer’
James
,
W.
,
+8 authors
O’malley
2005
Corpus ID: 34437835
Inactivation of the tumor suppressor gene (cid:1)j6Th(cid:1)(cid:1)(4(cid:1) is the most common genetic alteration in human head…
Expand
2005
2005
Growth Inhibitory Effect of Inter 1 eron-Is Associated with the Induction of Cyclin-dependent Kinase Inhibitor p 2 lkuPl in a Human Gastric Carcinoma Cell Line 1
H. Kuniyasu
,
W. Yasui
,
+6 authors
E. Tahara
2005
Corpus ID: 14977431
The effect of IFN-fi on cell growth and the mechanism of growth modulation was examined in human gastric carcinoma cell lines…
Expand
1999
1999
Melanoma development in relation to non-functional p16/INK4A protein and dysplastic naevus syndrome in Swedish melanoma kindreds.
J. Hashemi
,
Stig Linder
,
A. Platz
,
Johan Hansson
Melanoma research
1999
Corpus ID: 38232629
The CDKN2A gene encodes the cell cycle inhibitor p16/ INK4A, which is involved in familial cutaneous melanoma. We have studied…
Expand