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CDH1 gene

Known as: ECAD, CADHERIN, EPITHELIAL, Cadherin 1, Type 1, E-Cadherin (Epithelial) Gene 
This gene plays a role in cell-cell adhesion and loss of function contributes to the progression of many carcinomas.
National Institutes of Health

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Related topics

18 relations
Atypical Lobular Breast HyperplasiaCDH1 protein, humanCarcinoma, LobularCell Adhesion

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CDH1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2007
Review
2007
The role of uvomorulin in the formation of epithelial occluding junctions.
We have used an assay for the recovery of transepithelial resistance to identify proteins involved in the formation of the… 
2002
2002
Epithelial-type and neural-type cadherin expression in malignant noncarcinomatous neoplasms with epithelioid features that involve the soft tissues.
CONTEXT Transmembrane adhesion molecules, epithelial-type cadherin (ECAD) and neural-type cadherin (NCAD), help in regulating… 
Highly Cited
2001
Highly Cited
2001
Localization of IQGAP1 is inversely correlated with intercellular adhesion mediated by e‐cadherin in gastric cancers
Down‐regulation of E‐cadherin function is characteristic of cancer cells and might involve the small G‐protein Rho family… 
Highly Cited
1999
Highly Cited
1999
WT1 expression induces features of renal epithelial differentiation in mesenchymal fibroblasts
The WT1 tumor suppressor gene, implicated in hereditofamilial and sporadic Wilms' tumor, is required for normal renal development… 
1995
1995
Cadherin transfection of Xenopus XTC cells downregulates expression of substrate adhesion molecules
Cadherins are discussed not in terms of their adhesive function but rather as morphoregulatory proteins. Changes in gene… 
Highly Cited
1994
Highly Cited
1994
Paracellular barrier and junctional protein distribution depend on basolateral extracellular Ca2+ in cultured epithelia.
Highly Cited
1992
Highly Cited
1992
Association of Intercellular Adhesion Moleculeq (ICAM-1) with Actin-containing Cytoskeleton and -actinin
We have studied the cytoskeletal association of intercellular adhesion molecule-1 (ICAM-1, CD54), an integral membrane protein… 
Review
1989
Review
1989
Uvomorulin‐catenin complex: Cytoplasmic anchorage of a Ca2+‐dependent cell adhesion molecule
The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins, named catenins, which… 
Highly Cited
1989
Highly Cited
1989
Membrane domains of intestinal epithelial cells: distribution of Na+,K+- ATPase and the membrane skeleton in adult rat intestine during fetal development and after epithelial isolation
The organization of the basolateral membrane domain of highly polarized intestinal absorptive cells was studied in adult rat… 
1986
1986
Molecular cloning of the mouse cell adhesion molecule uvomorulin: cDNA contains a B1-related sequence.
A clone (F20) containing coding sequences for the cell adhesion molecule uvomorulin was isolated by immunological techniques from… 
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