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CDC42 gene

Known as: GTP-BINDING PROTEIN, 25-KD, G25K, GTP binding protein, 25kDa 
This gene is involved in the regulation of the actin cytoskeleton.
National Institutes of Health

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CDC42 wt Allele
Cell Cycle ControlEndocytosisGTP Bindingcdc42 GTP-Binding Protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Long-Term Nitric Oxide Exposure Enhances Lung Cancer Cell Migration
Nitric oxide (NO) found in the vicinity of lung cancer cells may play a role in the regulation of cancer cell behaviors. To… 
Review
2006
Review
2006
mPar6α Controls Neuronal Migration
We review studies on the polarity of developing cerebellar granule, showing that the centrosome localizes to the pole of the… 
2004
2004
Platelet storage under in vitro condition is associated with calcium-dependent apoptosis-like lesions and novel reorganization in platelet cytoskeleton.
Highly Cited
2001
Highly Cited
2001
ATP-binding cassette transporter-1 induces rearrangement of actin cytoskeletons possibly through Cdc42/N-WASP.
Positional cloning approaches revealed that Tangier disease (TD), a genetic high density lipoprotein deficiency, is associated… 
2000
2000
Structure of the complex of Cdc42Hs with a peptide derived from P-21 activated kinase.
Cdc42Hs is a member of the Ras superfamily of GTPases and initiates a cascade that begins with the activation of several kinases… 
Highly Cited
1999
Highly Cited
1999
Involvement of Cdc42 small G protein in cell-cell adhesion, migration and morphology of MDCK cells
The Rho small G protein family consists of the Rho, Rac, and Cdc42 subfamilies and regulates various cell functions through… 
1998
1998
Fluoride Activation of the Rho Family GTP-binding Protein Cdc42Hs*
Aluminum tetrafluoride (AlF4 −) activation of heterotrimeric G-protein α-subunits is a well established aspect of the… 
1997
1997
Increased Activity of Small GTP-binding Protein-dependent Phospholipase D during Differentiation in Human Promyelocytic Leukemic HL60 Cells*
In response to dibutyryl cyclic AMP (dbcAMP) and all-trans retinoic acid, human promyelocytic leukemic HL60 cells differentiate… 
Highly Cited
1995
Highly Cited
1995
A 68-kDa Kinase and NADPH Oxidase Component p67 Are Targets for Cdc42Hs and Rac1 in Neutrophils (*)
Cdc42Hs and Rac1 are members of the Ras superfamily of small molecular weight (p21) GTP binding proteins. Cdc42Hs induces… 
Highly Cited
1995
Highly Cited
1995
Characterization of the Effector-specifying Domain of Rac Involved in NADPH Oxidase Activation (*)
Production of microbicidal oxidants by phagocytic leukocytes requires activation of a latent NADPH oxidase by the coordinated… 
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