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CDC42 gene

Known as: GTP-BINDING PROTEIN, 25-KD, G25K, GTP binding protein, 25kDa 
This gene is involved in the regulation of the actin cytoskeleton.
National Institutes of Health

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CDC42 wt Allele
Cell Cycle ControlEndocytosisGTP Bindingcdc42 GTP-Binding Protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Intrinsic GTP hydrolysis is observed for a switch 1 variant of Cdc42 in the presence of a specific GTPase inhibitor
ABSTRACT The Ras-related protein Cell division cycle 42 (Cdc42) is important in cell-signaling processes. Protein interactions… 
2015
2015
Downregulation of miR-25 modulates non-small cell lung cancer cells by targeting CDC42
The current study aims to investigate the fuctional role of miRNA-25 in non-small cell lung cancer (NSCLC) cells. Quantitative… 
2012
2012
Functional investigation of a schizophrenia GWAS signal at the CDC42 gene
Abstract Objectives. SNP rs2473277 upstream of the cell division cycle 42 (CDC42) gene was associated with schizophrenia in a… 
2011
2011
Retinal degeneration modulates intracellular localization of CDC42 in photoreceptors
Purpose Rho GTPases such as RAS-related C3 botulinum substrate 1 (RAC1) and cell division cycle 42 homolog (S. cerevisiae; CDC42… 
Review
2006
Review
2006
mPar6α Controls Neuronal Migration
We review studies on the polarity of developing cerebellar granule, showing that the centrosome localizes to the pole of the… 
2004
2004
Backbone dynamics of an oncogenic mutant of Cdc42Hs shows increased flexibility at the nucleotide-binding site.
Cdc42Hs, a member of the Ras superfamily of GTP-binding signal transduction proteins, binds guanine nucleotides, and acts as a… 
2000
2000
Structure of the complex of Cdc42Hs with a peptide derived from P-21 activated kinase.
Cdc42Hs is a member of the Ras superfamily of GTPases and initiates a cascade that begins with the activation of several kinases… 
1998
1998
Fluoride Activation of the Rho Family GTP-binding Protein Cdc42Hs*
Aluminum tetrafluoride (AlF4 −) activation of heterotrimeric G-protein α-subunits is a well established aspect of the… 
1997
1997
Increased Activity of Small GTP-binding Protein-dependent Phospholipase D during Differentiation in Human Promyelocytic Leukemic HL60 Cells*
In response to dibutyryl cyclic AMP (dbcAMP) and all-trans retinoic acid, human promyelocytic leukemic HL60 cells differentiate… 
Highly Cited
1995
Highly Cited
1995
Characterization of the Effector-specifying Domain of Rac Involved in NADPH Oxidase Activation (*)
Production of microbicidal oxidants by phagocytic leukocytes requires activation of a latent NADPH oxidase by the coordinated… 
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