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CD45 Antigens

Known as: Leukocyte Common Antigens, CD45, Leukocyte common Ag 
High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain two FIBRONECTIN… 
National Institutes of Health

Related topics

Related topics

23 relations

Narrower (6)

B220 AntigensCD45RA AntigensCD45RB AntigensPTPRC protein, human

Broader (3)

CD AntigensHistocompatibility AntigensProtein phosphatase
CD45 Ag:PrThr:Pt:Tiss:Ord:Immune stainCD45 negative events:Num:Pt:XXX:QnCD45 positive events:Num:Pt:XXX:QnCD45RO Antigens

Papers overview

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Highly Cited
1999
Highly Cited
1999
Galectin-1, a natural ligand for the receptor-type protein tyrosine phosphatase CD45.
Highly Cited
1997
Highly Cited
1997
T cells of the human intestinal lamina propria are high producers of interleukin-10
Background and aim —Some of the recently observed functional features characteristic of immunocompetent cells residing in the… 
Highly Cited
1995
Highly Cited
1995
A one-step procedure for biotinylation and chemical cross-linking of lymphocyte surface and intracellular membrane-associated molecules.
The use of cell surface biotinylation has become a popular alternative to radioiodination in studies involving labeling of cell… 
Highly Cited
1991
Highly Cited
1991
The B lymphocyte adhesion molecule CD22 interacts with leukocyte common antigen CD45RO on T cells and α2–6 sialyltransferase, CD75, on B cells
Highly Cited
1991
Highly Cited
1991
Coassociation of CD26 (dipeptidyl peptidase IV) with CD45 on the surface of human T lymphocytes.
In the present report, we demonstrated that modulation of CD26 from T cell surface induced by antiCD26 (1F7) led to enhanced… 
Highly Cited
1990
Highly Cited
1990
Dephosphorylation and activation of the T cell tyrosine kinase pp56lck by the leukocyte common antigen (CD45).
pp56lck, encoded by the lck proto-oncogene, is a non-receptor tyrosine protein kinase (TPK) found in all T lymphocytes. A… 
Highly Cited
1990
Highly Cited
1990
Coclustering CD45 with CD4 or CD8 alters the phosphorylation and kinase activity of p56lck
Antibody-mediated CD4 crosslinking results in increased tyrosine phosphorylation and tyrosine kinase activity of the associated… 
Highly Cited
1988
Highly Cited
1988
Loss of CD45R (Lp220) represents a post-thymic T cell differentiation event.
CD45R+ and CDw29+ CD4+ T cells are widely regarded as separate functionally defined T cell lineages. The work described here… 
Highly Cited
1988
Highly Cited
1988
CD45 regulates signal transduction and lymphocyte activation by specific association with receptor molecules on T or B cells.
Evidence is presented that the leukocyte common antigen CD45 can regulate both signal transduction by lymphocyte receptor… 
Highly Cited
1985
Highly Cited
1985
Hodgkin's disease, lymphocyte predominance type, nodular--a distinct entity? Unique staining profile for L&H variants of Reed-Sternberg cells defined by monoclonal antibodies to leukocyte common…
Using monoclonal antibodies to leukocyte common antigen, granulocyte-related antigen, and B-cell specific antigens, L&H variants… 
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