Skip to search formSkip to main contentSkip to account menu

CD45 Antigens

Known as: Leukocyte Common Antigens, CD45, Leukocyte common Ag 
High-molecular weight glycoproteins uniquely expressed on the surface of LEUKOCYTES and their hemopoietic progenitors. They contain two FIBRONECTIN… 
National Institutes of Health

Related topics

Related topics

23 relations

Narrower (6)

B220 AntigensCD45RA AntigensCD45RB AntigensPTPRC protein, human

Broader (3)

CD AntigensHistocompatibility AntigensProtein phosphatase
CD45 Ag:PrThr:Pt:Tiss:Ord:Immune stainCD45 negative events:Num:Pt:XXX:QnCD45 positive events:Num:Pt:XXX:QnCD45RO Antigens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1995
Highly Cited
1995
A one-step procedure for biotinylation and chemical cross-linking of lymphocyte surface and intracellular membrane-associated molecules.
The use of cell surface biotinylation has become a popular alternative to radioiodination in studies involving labeling of cell… 
Highly Cited
1992
Highly Cited
1992
Both T cell receptor (TcR)‐CD3 complex and CD2 increase the tyrosine kinase activity of p56lck. CD2 can mediate TcR‐CD3‐independent and CD45‐dependent activation of p56lck
T cell activation by triggering the T cell receptor (TcR)‐CD3 complex leads to a dramatic increase in tyrosine phosphorylation of… 
Highly Cited
1992
Highly Cited
1992
Isoform‐specific associations of CD45 with accessory molecules in human T lymphocytes
Association of CD45 with surface molecules was investigated in human T lymphocytes by co‐capping. CD45 appeared to be associated… 
Highly Cited
1990
Highly Cited
1990
CD45, an integral membrane protein tyrosine phosphatase. Characterization of enzyme activity.
Highly Cited
1990
Highly Cited
1990
Activation of tyrosine phosphorylation in human T cells via the CD2 pathway. Regulation by the CD45 tyrosine phosphatase.
In this study we compare the effect of CD3 and CD2 ligation on tyrosine kinase activation in human peripheral blood T cells… 
Highly Cited
1989
Highly Cited
1989
Definition of the thymic generative lineage by selective expression of high molecular weight isoforms of CD45 (T200)
Selective expression of CD45 isoforms distinguishes naive and memory T cells in peripheral blood. Paradoxically, although the… 
Highly Cited
1988
Highly Cited
1988
Comparative biochemical and tissue distribution study of four distinct CD45 antigen specificities.
Studies on the antigenic structure of the human CD45 glycoproteins using mAb have revealed the existence of four reactivity… 
Highly Cited
1985
Highly Cited
1985
Hodgkin's disease, lymphocyte predominance type, nodular--a distinct entity? Unique staining profile for L&H variants of Reed-Sternberg cells defined by monoclonal antibodies to leukocyte common…
Using monoclonal antibodies to leukocyte common antigen, granulocyte-related antigen, and B-cell specific antigens, L&H variants… 
Highly Cited
1984
Highly Cited
1984
Origin of the rat mesangial phagocyte and its expression of the leukocyte common antigen.
We have previously characterized a subpopulation of cells in the rat glomerular mesangium that are phagocytic, display Ia… 
Highly Cited
1984
Highly Cited
1984
Modulation of Ia and leukocyte common antigen expression in rat glomeruli during the course of glomerulonephritis and aminonucleoside nephrosis.
We have investigated changes in the glomerular expression of two antigens, Ia and leukocyte common (LC) antigens, during the… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)