FAQ

Protein phosphatase

Known as: Phosphatases, Phosphoprotein, Protein Serine Threonine Phosphatase, Protein-Serine-Threonine Phosphatase 
Encoded by Protein Phosphatase Genes, Protein Phosphatase enzymes remove tyrosine-, serine-, or threonine-bound phosphate groups from many… (More)

Topic mentions per year

Topic mentions per year

1950-2017
020040019502016

Related topics

Related topics

44 relations

Narrower (15)

CD45 AntigensCalcineurin APpm1h protein, ratProtein Phosphatase 1
(More)
CalcineurinCell Cycle ProteinsDephosphorylationEnzyme Gene
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Broader (1)

Phosphoric Monoester Hydrolases

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Protein phosphatase
Hydrolysis
physiological aspects
Hydrolase
Phosphoric Monoester Hydrolases
phosphoric monoester hydrolase activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
PHLPP: a phosphatase that directly dephosphorylates Akt, promotes apoptosis, and suppresses tumor growth.
Akt/protein kinase B critically regulates the balance between cell survival and apoptosis. Phosphorylation of Akt at two key… (More)
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Highly Cited
2003
Highly Cited
2003
Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis.
The precise mechanistic relationship between gene activation and repression events is a central question in mammalian… (More)
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Highly Cited
1994
Highly Cited
1994
Involvement of a calcineurin/inhibitor-1 phosphatase cascade in hippocampal long-term depression.
Long-term potentiation (LTP) is a synaptic mechanism thought to be involved in learning and memory. Long-term depression (LTD… (More)
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Highly Cited
1993
Highly Cited
1993
Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2.
We used the interaction trap, a yeast genetic selection for interacting proteins, to isolate human cyclin-dependent kinase… (More)
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Highly Cited
1993
Highly Cited
1993
The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit.
The retinoblastoma protein (p110RB) interacts with many cellular proteins in complexes potentially important for its growth… (More)
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Highly Cited
1993
Highly Cited
1993
Ceramide activates heterotrimeric protein phosphatase 2A.
Ceramide activates a cytosolic protein phosphatase present in rat T9 glioma cells and rat brain. Ceramide-activated protein… (More)
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Highly Cited
1993
Highly Cited
1993
An essential role for protein phosphatases in hippocampal long-term depression.
The effectiveness of long-term potentiation (LTP) as a mechanism for information storage would be severely limited if processes… (More)
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Highly Cited
1992
Highly Cited
1992
Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation.
Extracellular signals that promote cell growth activate cascades of protein kinases. The kinases are dephosphorylated and… (More)
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Highly Cited
1990
Highly Cited
1990
Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants.
The cyclic heptapeptide, microcystin-LR, inhibits protein phosphatases 1 (PP1) and 2A (PP2A) with Ki values below 0.1 nM. Protein… (More)
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Highly Cited
1989
Highly Cited
1989
Calyculin A and okadaic acid: inhibitors of protein phosphatase activity.
Calyculin A and okadaic acid induce contraction in smooth muscle fibers. Okadaic acid is an inhibitor of phosphatase activity and… (More)
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