CD45RA Antigens

Known as: Receptor-Type Tyrosine-Protein Phosphatase C Isoform CD45RA, Antigens, 2H4, CD45RA 
CD45RA is encoded by the human PTPRC gene. This protein plays a role in both lymphocyte function and protein dephosphorylation. It is an isoform of… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Although human naturally occurring regulatory T cells (Tregs) may express either CD45RA or CD45RO, we find in agreement with… (More)
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Highly Cited
2006
Highly Cited
2006
Abnormalities in CD4(+)CD25(+)Foxp3(+) regulatory T (T reg) cells have been implicated in susceptibility to allergic, autoimmune… (More)
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Highly Cited
2003
Highly Cited
2003
Four human CD8+ T-cell subsets, naive (CCR7+CD45RA+), central memory (TCM, CCR7+CD45RA-), effector memory (TEM, CCR7-CD45RA… (More)
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Highly Cited
2003
Highly Cited
2003
PURPOSE T cells constitutively expressing both CD4 and CD25are essential for maintenance of self-tolerance and therefore have… (More)
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Highly Cited
2003
Highly Cited
2003
Recent studies in mice have shown that although interleukin 15 (IL-15) plays an important role in regulating homeostasis of… (More)
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Highly Cited
2001
Highly Cited
2001
Understanding the lineage differentiation of memory T cells is a central question in immunology. We investigated this issue by… (More)
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Highly Cited
1999
Highly Cited
1999
We recently showed that circulating human CD8(+) effector cells have a CD45RA+CD27(-) membrane phenotype. In itself this… (More)
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Highly Cited
1997
Highly Cited
1997
Human CD8+ memory- and effector-type T cells are poorly defined. We show here that, next to a naive compartment, two discrete… (More)
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Highly Cited
1997
Highly Cited
1997
A subset of CD4+CD11c-CD3- blood cells was recently shown to develop into dendritic cells when cultured with monocyte conditioned… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND Inadequate reconstitution of CD4+ T lymphocytes is an important clinical problem complicating chemotherapy, human… (More)
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