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CCNT1 gene

Known as: CDK9-ASSOCIATED C-TYPE CYCLIN, CYCLIN T, CYCLIN C-RELATED PROTEIN 
National Institutes of Health

Related topics

Related topics

1 relation
HIVEP1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation
Significance Transcriptional elongation by RNA polymerase II produces full-length RNA transcripts and plays a general and… 
Highly Cited
2010
Highly Cited
2010
HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP.
Highly Cited
2007
Highly Cited
2007
Differential Chromatin Looping Regulates CD4 Expression in Immature Thymocytes
ABSTRACT Runx1 binds the silencer and represses CD4 transcription in immature thymocytes. In this study, using looping chromatin… 
2004
2004
Evidence for conformational flexibility in the Tat-TAR recognition motif of cyclin T1.
Highly Cited
2003
Highly Cited
2003
Tat and Trans-activation-responsive (TAR) RNA-independent Induction of HIV-1 Long Terminal Repeat by Human and Murine Cyclin T1 Requires Sp1*
P-TEFb, cyclin T1 + CDK9, is needed for the expression of cellular promoters and primate lentiviral long terminal repeats (LTRs… 
Highly Cited
2002
Highly Cited
2002
P-TEFb Containing Cyclin K and Cdk9 Can Activate Transcription via RNA*
Different positive transcription elongation factor b (P-TEFb) complexes isolated from mammalian cells contain a common catalytic… 
Highly Cited
2002
Highly Cited
2002
Specific HIV-1 TAR RNA loop sequence and functional groups are required for human cyclin T1-Tat-TAR ternary complex formation.
Replication of human immunodeficiency virus requires Tat protein which activates elongation of RNA polymerase II transcription at… 
2001
2001
Distinct regions of cyclinT1 are required for binding to CDK9 and for recruitment to the HIV‐1 Tat/TAR complex
Tat‐mediated activation of the HIV‐1 promoter activity requires Tat‐dependent recruitment of the cyclinT1/CDK9 complex (P‐TEFb… 
Highly Cited
2000
Highly Cited
2000
HIV-1 TAR RNA Enhances the Interaction between Tat and Cyclin T1*
Human immunodeficiency virus, type 1 (HIV-1), Tat activates elongation of RNA polymerase II transcription at the HIV-1 promoter… 
1999
1999
Analysis of the Effect of Natural Sequence Variation in Tat and in Cyclin T on the Formation and RNA Binding Properties of Tat-Cyclin T Complexes
ABSTRACT The biological activity of the human immunodeficiency virus type 1 (HIV-1) Tat (Tat1) transcriptional activator requires… 
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