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CCNT1 gene

Known as: CDK9-ASSOCIATED C-TYPE CYCLIN, CYCLIN T, CYCLIN C-RELATED PROTEIN 
National Institutes of Health

Related topics

Related topics

1 relation
HIVEP1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
CCNT1 mediates mTor inhibitor related antiviral effects in HCV genotype 2a
2017
2017
MD simulation of the Tat/Cyclin T1/CDK9 complex revealing the hidden catalytic cavity within the CDK9 molecule upon Tat binding
In this study, we applied molecular dynamics (MD) simulation to analyze the dynamic behavior of the Tat/CycT1/CDK9 tri-molecular… 
2015
2015
Molecular Dynamics Simulation and Experimental Verification of the Interaction between Cyclin T1 and HIV-1 Tat Proteins
The viral encoded Tat protein is essential for the transcriptional activation of HIV proviral DNA. Interaction of Tat with a… 
2008
2008
Dominant negative mutant cyclin T1 proteins that inhibit HIV transcription by forming a kinase inactive complex with Tat.
Transcription of the human immunodeficiency virus type 1 (HIV) requires the interaction of the cyclin T1 (CycT1) subunit of a… 
2004
2004
Evidence for conformational flexibility in the Tat-TAR recognition motif of cyclin T1.
2004
2004
Transcriptional activity and substrate recognition of cyclin T2 from P-TEFb.
2003
2003
Development of a mouse model for HIV/AIDS.
A small animal model would be very valuable for HIV/AIDS vaccine testing, investigating HIV pathophysiology, and exploring anti… 
Highly Cited
2002
Highly Cited
2002
P-TEFb Containing Cyclin K and Cdk9 Can Activate Transcription via RNA*
Different positive transcription elongation factor b (P-TEFb) complexes isolated from mammalian cells contain a common catalytic… 
2002
2002
Cyclin T1 Expression Is Mediated by a Complex and Constitutively Active Promoter and Does Not Limit Human Immunodeficiency Virus Type 1 Tat Function in Unstimulated Primary Lymphocytes
ABSTRACT Cyclin T1 (CycT1), a component of positive-transcription-elongation factor-b (P-TEFb), is an essential cofactor for… 
2001
2001
Distinct regions of cyclinT1 are required for binding to CDK9 and for recruitment to the HIV‐1 Tat/TAR complex
Tat‐mediated activation of the HIV‐1 promoter activity requires Tat‐dependent recruitment of the cyclinT1/CDK9 complex (P‐TEFb… 
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