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CCNT1 gene

Known as: CDK9-ASSOCIATED C-TYPE CYCLIN, CYCLIN T, CYCLIN C-RELATED PROTEIN 
 
National Institutes of Health

Related topics

Related topics

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HIVEP1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNP.
HIV-1 transactivator Tat has greatly contributed to our understanding of transcription elongation by RNAPII. We purified HIV-1… Expand
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2008
2008
Differential chromatin looping regulates CD4 expression in immature thymocytes.
Runx1 binds the silencer and represses CD4 transcription in immature thymocytes. In this study, using looping chromatin… Expand
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2008
2008
Dominant negative mutant Cyclin T1 proteins inhibit HIV transcription by specifically degrading Tat
BackgroundThe positive transcription elongation factor b (P-TEFb) is an essential cellular co-factor for the transcription of the… Expand
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2004
2004
Evidence for conformational flexibility in the Tat-TAR recognition motif of cyclin T1.
Cyclin T1 (CycT1) is a cellular transcription elongation factor that also participates in Tat-mediated activation of several… Expand
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Highly Cited
2003
Highly Cited
2003
Tat and trans-activation-responsive (TAR) RNA-independent induction of HIV-1 long terminal repeat by human and murine cyclin T1 requires Sp1.
P-TEFb, cyclin T1 + CDK9, is needed for the expression of cellular promoters and primate lentiviral long terminal repeats (LTRs… Expand
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2002
2002
Specific HIV-1 TAR RNA loop sequence and functional groups are required for human cyclin T1-Tat-TAR ternary complex formation.
Replication of human immunodeficiency virus requires Tat protein which activates elongation of RNA polymerase II transcription at… Expand
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2002
2002
P-TEFb containing cyclin K and Cdk9 can activate transcription via RNA.
Different positive transcription elongation factor b (P-TEFb) complexes isolated from mammalian cells contain a common catalytic… Expand
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2001
2001
Distinct regions of cyclinT1 are required for binding to CDK9 and for recruitment to the HIV-1 Tat/TAR complex.
Tat-mediated activation of the HIV-1 promoter activity requires Tat-dependent recruitment of the cyclinT1/CDK9 complex (P-TEFb… Expand
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2000
2000
HIV-1 TAR RNA enhances the interaction between Tat and cyclin T1.
Human immunodeficiency virus, type 1 (HIV-1), Tat activates elongation of RNA polymerase II transcription at the HIV-1 promoter… Expand
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1999
1999
Analysis of the effect of natural sequence variation in Tat and in cyclin T on the formation and RNA binding properties of Tat-cyclin T complexes.
The biological activity of the human immunodeficiency virus type 1 (HIV-1) Tat (Tat1) transcriptional activator requires the… Expand
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