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CCND1 protein, human

Known as: PRAD1 oncogene protein, human, D11S287E, BCL-1 oncogene protein, human 
G1/S-specific cyclin-D1 (295 aa, ~34 kDa) is encoded by the human CCND1 gene. This protein is involved in the regulation of the G1/S transition of… 
National Institutes of Health

Related topics

Related topics

16 relations
BCL1BTG Cell Cycle Regulation PathwayBeta-Catenin Accumulation PathwayCCND1 gene

Broader (1)

Cyclin D1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
circRNA circ‐CCND1 promotes the proliferation of laryngeal squamous cell carcinoma through elevating CCND1 expression via interacting with HuR and miR‐646
Cyclin D1 (CCND1) is a well‐known proliferation promoter that accelerates G1/S transition in cancer. However, the underlying… 
Highly Cited
2016
Highly Cited
2016
Evaluation of CCND1 amplification and CyclinD1 expression: diffuse and strong staining of CyclinD1 could have same predictive roles as CCND1 amplification in ER positive breast cancers.
CCND1 is amplified in around 10-20% of primary breast cancers and preferentially occurs in ER positive tumors. Though CCND1… 
Highly Cited
2014
Highly Cited
2014
Dihydroartemisinin inhibits cell proliferation via AKT/GSK3β/cyclinD1 pathway and induces apoptosis in A549 lung cancer cells.
Lung cancer is the most common cause of cancer-related death in the world. The main types of lung cancer are small cell lung… 
Highly Cited
2011
Highly Cited
2011
CCND1 as a Predictive Biomarker of Neoadjuvant Chemotherapy in Patients with Locally Advanced Head and Neck Squamous Cell Carcinoma
Background Cyclin D1 (CCND1) has been associated with chemotherapy resistance and poor prognosis. In this study, we tested the… 
Highly Cited
2003
Highly Cited
2003
Rearrangements and increased expression of cyclin D1 (CCND1) in neuroblastoma
Cyclin D1 regulates G1 cell cycle progression by controlling the phosphorylation of the retinoblastoma protein. This pathway is… 
Highly Cited
2000
Highly Cited
2000
Characterization of the Minimal Replicon of a Cryptic Deinococcus radiodurans SARK Plasmid and Development of Versatile Escherichia coli-D. radiodurans Shuttle Vectors
ABSTRACT The nucleotide sequence of a 12-kb fragment of the crypticDeinococcus radiodurans SARK plasmid pUE10 was determined, in… 
Highly Cited
1995
Highly Cited
1995
Abnormalities in the PRAD1 (CYCLIN D1 / BCL‐1) oncogene are frequent in cervical and vulvar squamous cell carcinoma cell lines
Background. CYCLIN D1, a cell‐cycle control gene, recently has been shown to be identical to an oncogene alternatively known as… 
Highly Cited
1993
Highly Cited
1993
PRAD1/lCyclin D1 proto‐oncogene: Genomic organization, 5′ dna sequence, and sequence of a tumor‐specific rearrangement breakpoint
PRAD1 (previously D11S287) is a putative proto‐oncogene at 11q13, activated by overexpression through gene rearrangement or gene… 
Highly Cited
1992
Highly Cited
1992
Characterization of chromosome 11 translocation breakpoints at the bcl-1 and PRAD1 loci in centrocytic lymphoma.
The chromosome 11q13 bcl-1 locus is rearranged in the majority of centrocytic lymphomas, a CD5-positive B-cell non-Hodgkins… 
Highly Cited
1991
Highly Cited
1991
Rearrangement and overexpression of D11S287E, a candidate oncogene on chromosome 11q13 in benign parathyroid tumors.
We report the detailed molecular characterization of a human parathyroid adenoma with a clonal parathyroid hormone gene… 
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