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CCL5 protein, human

Known as: MGC17164, Chemokine (C-C Motif) Ligand 5, RANTES 
C-C motif chemokine 5 (91 aa, ~10 kDa) is encoded by the human CCL5 gene. This protein plays a role in both the release of histamine and… 
National Institutes of Health

Related topics

Related topics

21 relations
Antiviral ResponseBiologic DevelopmentCCL5 geneCCL5 wt Allele

Broader (1)

RANTES

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
The role of infiltrating immune cells in dysfunctional adipose tissue
Abstract Adipose tissue (AT) dysfunction, characterized by loss of its homeostatic functions, is a hallmark of non-communicable… 
Highly Cited
2012
Highly Cited
2012
MicroRNAs reprogram normal fibroblasts into cancer-associated fibroblasts in ovarian cancer.
UNLABELLED Cancer-associated fibroblasts (CAF) are a major constituent of the tumor stroma, but little is known about how cancer… 
Highly Cited
2010
Highly Cited
2010
MicroRNA-125a contributes to elevated inflammatory chemokine RANTES levels via targeting KLF13 in systemic lupus erythematosus.
OBJECTIVE MicroRNA (miRNA) have received increasing attention as posttranscriptional regulators that fine-tune the homeostasis of… 
Highly Cited
2000
Highly Cited
2000
Multiple Regulatory Domains Control IRF-7 Activity in Response to Virus Infection*
Recent studies implicate the interferon regulatory factors (IRF), IRF-3 and IRF-7, as key activators of Type 1 interferon genes… 
Highly Cited
1999
Highly Cited
1999
Polymorphism in RANTES chemokine promoter affects HIV-1 disease progression.
RANTES (regulated on activation normal T cell expressed and secreted) is one of the natural ligands for the chemokine receptor… 
Highly Cited
1998
Highly Cited
1998
Aminooxypentane-RANTES Induces CCR5 Internalization but Inhibits Recycling: A Novel Inhibitory Mechanism of HIV Infectivity
CCR5, a chemokine receptor expressed on T cells and macrophages, is the principal coreceptor for M-tropic HIV-1 strains. Recently… 
Highly Cited
1998
Highly Cited
1998
Chemokine Sequestration by Viral Chemoreceptors as a Novel Viral Escape Strategy: Withdrawal of Chemokines from the Environment of Cytomegalovirus-infected Cells
Human cytomegalovirus (HCMV), a betaherpesvirus, has developed several ways to evade the immune system, notably downregulation of… 
Highly Cited
1998
Highly Cited
1998
IL-4 induces eotaxin: a possible mechanism of selective eosinophil recruitment in helminth infection and atopy.
A common feature of some parasitic infections and allergic and atopic skin diseases is the involvement of Th2 lymphocytes and the… 
Highly Cited
1997
Highly Cited
1997
In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression
Following the identification of the C-C chemokines RANTES, MIP-1α and MIP-1β as major human immunodeficiency virus (HIV… 
Highly Cited
1996
Highly Cited
1996
The amino-terminal extracellular domain of the MCP-1 receptor, but not the RANTES/MIP-1alpha receptor, confers chemokine selectivity. Evidence for a two-step mechanism for MCP-1 receptor activation.
The chemoattractant cytokines, MCP-1 (monocyte chemoattractant protein) and MIP-1alpha (macrophage inflammatory protein), are… 
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