D. Graham

Publications1,447
h-index145
Citations85,656
Highly Influential Citations2,225
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Management of Helicobacter pylori infection—the Maastricht IV/ Florence Consensus Report
TLDR
In this 4th edition of the Maastricht consensus report aspects related to the clinical role of H pylori were looked at again in 2010, with recommendations to guide doctors involved in the management of this infection associated with various clinical conditions. Expand
Current concepts in the management of Helicobacter pylori infection: the Maastricht III Consensus Report
TLDR
H pylori eradication is less effective than proton pump inhibitor (PPI) treatment in preventing ulcer recurrence in long term NSAID users and a test and treat strategy using a non-invasive test is recommended in adult patients with persistent dyspepsia under the age of 45. Expand
Management of Helicobacter pylori infection—the Maastricht V/Florence Consensus Report
TLDR
This fifth edition of the Maastricht Consensus Report describes how experts from 24 countries examined new data related to H. pylori infection in the various clinical scenarios and provided recommendations on the basis of the best available evidence and relevance. Expand
Traces of Human Migrations in Helicobacter pylori Populations
Helicobacter pylori, a chronic gastric pathogen of human beings, can be divided into seven populations and subpopulations with distinct geographical distributions. These modern populations derive… Expand
Expression, self-assembly, and antigenicity of the Norwalk virus capsid protein
TLDR
The availability of large amounts of recombinant Norwalk virus particles will allow the development of rapid, sensitive, and reliable tests for the diagnosis of Norwalkirus infection as well as the implementation of structural studies. Expand
Helicobacter pylori treatment in the era of increasing antibiotic resistance
TLDR
Clinicians should use ‘only use what works locally’ and ignore consensus statements and society guidelines if they are not consistent with local results, and try a 14 day concomitant quadruple treatment regimen if a highly effective regimen is not available locally. Expand
An African origin for the intimate association between humans and Helicobacter pylori
TLDR
It is established that anatomically modern humans were already infected by H. pylori before their migrations from Africa and demonstrate that H.pylori has remained intimately associated with their human host populations ever since. Expand
Norwalk Virus Shedding after Experimental Human Infection
TLDR
Noroviruses are shed in feces up to 8 weeks after infection and can be found in urine, faeces, and vomit up to a month after infection. Expand
Relationship between Helicobacter pylori iceA, cagA, and vacA Status and Clinical Outcome: Studies in Four Different Countries
TLDR
IceA status shows considerable geographic differences, and neither iceA nor combinations of iceA, vacA, andcagA were helpful in predicting the clinical presentation of an H. pylori infection. Expand
Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis: a randomized controlled trial.
TLDR
All dosages of celecoxib were efficacious in the treatment of rheumatoid arthritis and did not affect COX-1 activity in the GI tract mucosa as evidenced by less frequent incidence of endoscopic ulcers compared with naproxen. Expand
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