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CBLB gene

Known as: CAS-BR-M MURINE ECOTROPIC RETROVIRAL TRANSFORMING SEQUENCE B, Cbl proto-oncogene B, E3 ubiquitin protein ligase, Cbl-b 
This gene plays a role in the regulation of T cell activation.
National Institutes of Health

Related topics

Related topics

5 relations
Autoimmune DiseasesCBLB protein, humanDiabetes Mellitus, Insulin-DependentSignal Transduction

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Application of Artificial Neural Network for Prediction of Risk of Multiple Sclerosis Based on Single Nucleotide Polymorphism Genotypes
The artificial neural network (ANN) is a sort of machine learning method which has been used in determination of risk of human… 
2012
2012
Reinforcement of cancer immunotherapy by adoptive transfer of cblb‐deficient CD8+ T cells combined with a DC vaccine
The success of cancer immunotherapy is limited by potent endogenous immune‐evasion mechanisms, which are at least in part… 
2007
2007
Genetic Reconstitution of Autoimmune Type 1 Diabetes With Two Major Susceptibility Genes in the Rat
The Komeda diabetes-prone (KDP) rat is an animal model of human autoimmune type 1 diabetes. We have previously shown that two… 
2005
2005
A molecular dissection of lymphocyte unresponsiveness induced by sustained calcium signalling.
In lymphocytes, integration of Ca2+ and other signalling pathways results in productive activation, while unopposed Ca2… 
2004
2004
Haplotype tag single nucleotide polymorphism analysis of the human orthologues of the rat type 1 diabetes genes Ian4 (Lyp/Iddm1) and Cblb.
The diabetes-prone BioBreeding (BB) and Komeda diabetes-prone (KDP) rats are both spontaneous animal models of human autoimmune… 
2004
2004
Polymorphic variation in the CBLB gene in human type 1 diabetes
CBLB was evaluated as a candidate gene for type 1 diabetes (T1D) susceptibility based on its association with autoimmunity in… 
2000
2000
Properties of the Naturally Occurring Soluble Surface Glycoprotein of Ecotropic Murine Leukemia Virus: Binding Specificity and Possible Conformational Change after Binding to Receptor
ABSTRACT Ecotropic murine leukemia virus (MuLV) infection is initiated by the interaction between the surface glycoprotein (SU… 
Highly Cited
1998
Highly Cited
1998
The CBL-related Protein CBLB Participates in FLT3 and Interleukin-7 Receptor Signal Transduction in Pro-B Cells*
The FLT3 receptor tyrosine kinase and its ligand, FL, play an important role in early hematopoietic development. We have found… 
1994
1994
Characterization of epitopes defining two major subclasses of polytropic murine leukemia viruses (MuLVs) which are differentially expressed in mice infected with different ecotropic MuLVs
Polytropic murine leukemia viruses (MuLVs) arise in mice by recombination of ecotropic MuLVs with endogenous retroviral envelope… 
1984
1984
Differences in lymphomagenic properties of AKR mouse retroviruses.
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