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CBLB protein, human

Known as: RING Finger Protein 56, Cas-Br-M (murine) ecotropic retroviral transforming sequence b protein, human, RNF56 protein, human 
E3 ubiquitin-protein ligase CBL-B (982 aa, ~109 kDa) is encoded by the human CBLB gene. This protein plays a role in the ubiquitination of proteins.
National Institutes of Health

Papers overview

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2016
2016
Disseminated candidiasis has become one of the leading causes of hospital-acquired blood stream infections with high mobility and… Expand
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Highly Cited
2015
Highly Cited
2015
Aims/hypothesisThe therapeutic benefit of physical activity to prevent and treat type 2 diabetes is commonly accepted. However… Expand
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2012
2012
The Cbl family of RING finger ubiquitin ligases regulates signaling in many systems. Two new studies provide a structural basis… Expand
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Highly Cited
2011
Highly Cited
2011
Derivatives of cobalamin (vitamin B12) are required for activity of two enzymes in humans. Adenosylcobalamin is required for… Expand
Highly Cited
2011
Highly Cited
2011
Progression of chronic myelogenous leukemia (CML) to accelerated (AP) and blast phase (BP) is because of secondary molecular… Expand
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Highly Cited
2007
Highly Cited
2007
Isolated methylmalonic acidurias comprise a heterogeneous group of inborn errors of metabolism caused by defects of methylmalonyl… Expand
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Highly Cited
2007
Highly Cited
2007
The E3 ubiquitin ligase Cblb has a crucial role in the prevention of chronic inflammation and autoimmunity. Here we show that… Expand
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Highly Cited
2002
Highly Cited
2002
The autoimmune disease type 1 diabetes mellitus (insulin-dependent diabetes mellitus, IDDM) has a multifactorial etiology. So far… Expand
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Highly Cited
1998
Highly Cited
1998
The FLT3 receptor tyrosine kinase and its ligand, FL, play an important role in early hematopoietic development. We have found… Expand
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1986
1986
A patient has been described with methylmalonic aciduria because of an inability to release free vitamin B12 from lysosomes… Expand