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CBLB protein, human

Known as: RING Finger Protein 56, Cas-Br-M (murine) ecotropic retroviral transforming sequence b protein, human, RNF56 protein, human 
E3 ubiquitin-protein ligase CBL-B (982 aa, ~109 kDa) is encoded by the human CBLB gene. This protein plays a role in the ubiquitination of proteins.
National Institutes of Health

Related topics

Related topics

22 relations

Broader (2)

Adaptor Proteins, Signal TransducingProto-Oncogene Proteins c-cbl
Autoimmune DiseasesBinding ProteinsCBLB geneCell Nucleus

Papers overview

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2018
2018
Extractivismo urbano en Potosí, Ciudad Bolívar: un escenario de disputas socioambientales y defensa del territorio
El siguiente documento es un analisis de los conflictos socioambientales producidos por la actividad extractiva de Canteras… 
2016
2016
Assembly dynamics of the CBL and CBLB signalosomes
Figure EV1. T cells from CBL and CBLB mice develop and function normally. A Structure of the 30 end of the wild-type Cbl allele… 
2013
2013
Pharmacological chaperones as a potential therapeutic option in methylmalonic aciduria cblB type.
Methylmalonic aciduria (MMA) cblB type is caused by mutations in the MMAB gene. This encodes the enzyme ATP:cob(I)alamin… 
2012
2012
Cbl exposes its RING finger
The Cbl family of RING finger ubiquitin ligases regulates signaling in many systems. Two new studies provide a structural basis… 
2012
2012
CBL mutations in myeloproliferative neoplasms are also found in the gene’s proline-rich domain and in patients with the V617FJAK2
Background Despite the discovery of the p.V617F in JAK2, the molecular pathogenesis of some chronic myeloproliferative neoplasms… 
2010
2010
CBL, CBLB, TET2, ASXL1, and IDH1/2 Mutations as Well as Additional Chromosomal Aberrations Constitute Molecular Events Contributing to Malignant Progression In Advanced Philadelphia Chromosome…
Abstract 3396 Chronic myeloid leukemia (CML) is characterized by the BCR/ABL fusion gene. However, secondary molecular events… 
Highly Cited
1998
Highly Cited
1998
The CBL-related Protein CBLB Participates in FLT3 and Interleukin-7 Receptor Signal Transduction in Pro-B Cells*
The FLT3 receptor tyrosine kinase and its ligand, FL, play an important role in early hematopoietic development. We have found… 
1995
1995
Genetic Solutions to the Load Balancing Problem in ParallelComputers
EEcient use of resources in a parallel machine often requires the redistribution of tasks during the execution of applications… 
Review
1987
Review
1987
Inherited disorders of vitamin B12 metabolism.
1986
1986
Failure of lysosomal release of vitamin B12: a new complementation group causing methylmalonic aciduria (cblF).
A patient has been described with methylmalonic aciduria because of an inability to release free vitamin B12 from lysosomes… 
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