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CARD11 gene

Known as: CARMA1, BCL10-INTERACTING MAGUK PROTEIN 3, Caspase Recruitment Domain Family, Member 11 Gene 
This gene plays a role in apoptotic regulation.
National Institutes of Health

Related topics

Related topics

7 relations
ApoptosisCARD11 protein, humanCARD11 wt AlleleCaspase Recruitment Domain-Containing Protein 11

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
MiR-539 inhibits thyroid cancer cell migration and invasion by directly targeting CARMA1.
Highly Cited
2014
Highly Cited
2014
NOTCH1 Can Initiate NF-κB Activation via Cytosolic Interactions with Components of the T Cell Signalosome
T cell stimulation requires the input and integration of external signals. Signaling through the T cell receptor (TCR) is known… 
Highly Cited
2011
Highly Cited
2011
A20, ABIN-1/2, and CARD11 Mutations and Their Prognostic Value in Gastrointestinal Diffuse Large B-Cell Lymphoma
Purpose: Diffuse large B-cell lymphoma (DLBCL) is a heterogeneous group of aggressive lymphomas with the activated B-cell–like… 
Highly Cited
2010
Highly Cited
2010
c‐Rel but not NF‐κB1 is important for T regulatory cell development
Regulatory T (Treg) cells are crucial for maintaining peripheral tolerance and controlling T‐cell responses. The generation of… 
Highly Cited
2009
Highly Cited
2009
CARMA1 Controls an Early Checkpoint in the Thymic Development of FoxP3+ Regulatory T Cells1
Natural regulatory T cells (nTregs) that develop in the thymus are essential to limit immune responses and prevent autoimmunity… 
Highly Cited
2009
Highly Cited
2009
Commitment to the Regulatory T Cell Lineage Requires CARMA1 in the Thymus but Not in the Periphery
Regulatory T (Treg) cells expressing forkhead box P3 (Foxp3) arise during thymic selection among thymocytes with modestly self… 
Highly Cited
2009
Highly Cited
2009
Differential requirement for CARMA1 in agonist‐selected T‐cell development
Caspase recruitment domain‐containing membrane‐associated guanylate kinase protein‐1 (CARMA1) is a critical component of the NF… 
Highly Cited
2008
Highly Cited
2008
The Protein Kinase C-Responsive Inhibitory Domain of CARD11 Functions in NF-κB Activation To Regulate the Association of Multiple Signaling Cofactors That Differentially Depend on Bcl10 and MALT1 for…
ABSTRACT The activation of NF-κB by T-cell receptor (TCR) signaling is critical for T-cell activation during the adaptive immune… 
Highly Cited
2007
Highly Cited
2007
Regulation of NF-κB Activation in T Cells via Association of the Adapter Proteins ADAP and CARMA1
The adapter protein ADAP regulates T lymphocyte adhesion and activation. We present evidence for a previously unrecognized… 
Highly Cited
2004
Highly Cited
2004
The Molecular Adapter Carma1 Controls Entry of IκB Kinase into the Central Immune Synapse
Carma1 (also known as caspase recruitment domain [CARD]11, Bimp3) is a CARD-containing membrane-associated guanylate kinase… 
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